OBJECTIVE: The present study aimed to investigate the associations between residual symptoms of depression and specific self-reported symptoms in several cognitive domains. METHODS: The study investigated 117 patients with partially or fully remitted major depressive disorder (MDD) after treatment with antidepressant medications. RESULTS: Fatigue was significantly associated with inability to focus, alertness, and feeling "blue"; low interest and difficulty with concentration were associated with apathy. No associations were found between deficits in the cognitive domains considered and residual symptoms such as self-blaming, feeling worthless, feeling hopeless, having suicidal thoughts, difficulty with sleep, and lack of appetite. CONCLUSION: Among MDD remitted patients endorsing residual symptoms such as fatigue and feeling "blue", deficits in a range of cognitive domains should be carefully assessed and treated.
OBJECTIVE: The present study aimed to investigate the associations between residual symptoms of depression and specific self-reported symptoms in several cognitive domains. METHODS: The study investigated 117 patients with partially or fully remitted major depressive disorder (MDD) after treatment with antidepressant medications. RESULTS:Fatigue was significantly associated with inability to focus, alertness, and feeling "blue"; low interest and difficulty with concentration were associated with apathy. No associations were found between deficits in the cognitive domains considered and residual symptoms such as self-blaming, feeling worthless, feeling hopeless, having suicidal thoughts, difficulty with sleep, and lack of appetite. CONCLUSION: Among MDD remitted patients endorsing residual symptoms such as fatigue and feeling "blue", deficits in a range of cognitive domains should be carefully assessed and treated.
Authors: Ana Paula Jesus-Nunes; João Paulo Barreto Borges Coroa; Felipe Coelho Argolo; Tayne de Miranda Moreira; Mychelle Morais-de-Jesus; Roberta Ferrari Marback; Fernanda S Correia-Melo; Acioly L T Lacerda; Lucas C Quarantini Journal: Trends Psychiatry Psychother Date: 2021-01-22
Authors: Shawn M McClintock; Mustafa M Husain; Stephen R Wisniewski; Andrew A Nierenberg; Jonathan W Stewart; Madhukar H Trivedi; Ian Cook; David Morris; Diane Warden; Augustus John Rush Journal: J Clin Psychopharmacol Date: 2011-04 Impact factor: 3.153
Authors: Maren Nyer; David Mischoulon; Jonathan E Alpert; Daphne J Holt; Charlotte D Brill; Albert Yeung; Paola Pedrelli; Lee Baer; Christina Dording; Ilana Huz; Lauren Fisher; Maurizio Fava; Amy Farabaugh Journal: Ann Clin Psychiatry Date: 2015-05 Impact factor: 1.567