Literature DB >> 20394088

A scaffold-tree-merging strategy for prospective bioactivity annotation of gamma-pyrones.

Stefan Wetzel1, Wolfram Wilk, Samy Chammaa, Bianca Sperl, Anke G Roth, Aybike Yektaoglu, Steffen Renner, Thorsten Berg, Christoph Arenz, Athanassios Giannis, Tudor I Oprea, Daniel Rauh, Markus Kaiser, Herbert Waldmann.   

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Year:  2010        PMID： 20394088     DOI： 10.1002/anie.200906555

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  8 in total

Review 1.  Natural Products in the "Marketplace": Interfacing Synthesis and Biology.

Authors:  Benjamin J Huffman; Ryan A Shenvi
Journal:  J Am Chem Soc       Date:  2019-02-13       Impact factor: 15.419

2.  Synthesis and SAR of Lehualide B: a marine-derived natural product with potent anti-multiple myeloma activity.

Authors:  Valer Jeso; Chunying Yang; Michael D Cameron; John L Cleveland; Glenn C Micalizio
Journal:  ACS Chem Biol       Date:  2013-04-02       Impact factor: 5.100

Review 3.  Small Molecule Inhibitors Targeting Biosynthesis of Ceramide, the Central Hub of the Sphingolipid Network.

Authors:  Jan Skácel; Barbara S Slusher; Takashi Tsukamoto
Journal:  J Med Chem       Date:  2021-01-04       Impact factor: 7.446

4.  Palladium-catalyzed coupling reactions on functionalized 2-trifluoromethyl-4-chromenone scaffolds. Synthesis of highly functionalized trifluoromethyl-heterocycles.

Authors:  Javier Izquierdo; Atul D Jain; Sarki A Abdulkadir; Gary E Schiltz
Journal:  Synthesis (Stuttg)       Date:  2019-03       Impact factor: 3.157

5.  Nanomolar inhibitors of the transcription factor STAT5b with high selectivity over STAT5a.

Authors:  Nagarajan Elumalai; Angela Berg; Kalaiselvi Natarajan; Andrej Scharow; Thorsten Berg
Journal:  Angew Chem Int Ed Engl       Date:  2015-02-20       Impact factor: 15.336

6.  Development of Erasin: a chromone-based STAT3 inhibitor which induces apoptosis in Erlotinib-resistant lung cancer cells.

Authors:  Christian Lis; Stefan Rubner; Martin Roatsch; Angela Berg; Tyler Gilcrest; Darwin Fu; Elizabeth Nguyen; Anne-Marie Schmidt; Harald Krautscheid; Jens Meiler; Thorsten Berg
Journal:  Sci Rep       Date:  2017-12-12       Impact factor: 4.379

7.  Rational development of Stafib-2: a selective, nanomolar inhibitor of the transcription factor STAT5b.

Authors:  Nagarajan Elumalai; Angela Berg; Stefan Rubner; Linda Blechschmidt; Chen Song; Kalaiselvi Natarajan; Jörg Matysik; Thorsten Berg
Journal:  Sci Rep       Date:  2017-04-11       Impact factor: 4.379

8.  Scaffold Hunter: a comprehensive visual analytics framework for drug discovery.

Authors:  Till Schäfer; Nils Kriege; Lina Humbeck; Karsten Klein; Oliver Koch; Petra Mutzel
Journal:  J Cheminform       Date:  2017-05-11       Impact factor: 5.514
  8 in total

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