AIM: The aim of this study was to evaluate the relationship between age and cell adhesion molecule markers (E-cadherin and syndecan-1). MATERIALS AND METHODS: Forty-three cases of gastric carcinoma below the age of 50 were referred to our center in the period of 5 years (2003–2008). Forty-three gastric carcinoma above the age of 50 years were sex-matched with the first group. Expression of syndecan-1 and E-cadherin were evaluated by immunohistochemistry in a total of 86 gastric carcinomas accompanying with all the clinicopathological findings in each case. RESULTS: The expression of syndecan-1 and E-cadherin did not show significant difference between two age groups; in addition, there were no significant differences in all the clinicopathological findings in these two age groups. DISCUSSION: Gastric carcinoma in young and old age adults showed no significant difference in respect of the expression of cell adhesion molecule markers. Our result shows that young age alone cannot be predictive of more metastasis and invasion potential.
AIM: The aim of this study was to evaluate the relationship between age and cell adhesion molecule markers (E-cadherin and syndecan-1). MATERIALS AND METHODS: Forty-three cases of gastric carcinoma below the age of 50 were referred to our center in the period of 5 years (2003–2008). Forty-three gastric carcinoma above the age of 50 years were sex-matched with the first group. Expression of syndecan-1 and E-cadherin were evaluated by immunohistochemistry in a total of 86 gastric carcinomas accompanying with all the clinicopathological findings in each case. RESULTS: The expression of syndecan-1 and E-cadherin did not show significant difference between two age groups; in addition, there were no significant differences in all the clinicopathological findings in these two age groups. DISCUSSION: Gastric carcinoma in young and old age adults showed no significant difference in respect of the expression of cell adhesion molecule markers. Our result shows that young age alone cannot be predictive of more metastasis and invasion potential.
Authors: T E Buffart; B Carvalho; E Hopmans; V Brehm; E Klein Kranenbarg; T B M Schaaij-Visser; P P Eijk; N C T van Grieken; B Ylstra; C J H van de Velde; G A Meijer Journal: J Pathol Date: 2007-01 Impact factor: 7.996
Authors: Edaise M Silva; Maria D Begnami; José Humberto T G Fregnani; Adriane G Pelosof; Claudia Zitron; André L Montagnini; Fernando Augusto Soares Journal: Gastric Cancer Date: 2008-09-30 Impact factor: 7.370
Authors: Manuel B Braga-Neto; Jessica Gomes Carneiro; Alzira M de Castro Barbosa; Igor S Silva; Danielle C Maia; Felipe S Maciel; Rafael Jorge Alves de Alcântara; Paulo Roberto L Vasconscelos; Lucia L B C Braga Journal: BMC Cancer Date: 2018-02-05 Impact factor: 4.430
Authors: Simon Kind; Christina Merenkow; Franziska Büscheck; Katharina Möller; David Dum; Viktoria Chirico; Andreas M Luebke; Doris Höflmayer; Andrea Hinsch; Frank Jacobsen; Cosima Göbel; Sören Weidemann; Christoph Fraune; Christina Möller-Koop; Claudia Hube-Magg; Till S Clauditz; Ronald Simon; Guido Sauter; Waldemar Wilczak; Ahmed Abdulwahab Bawahab; Jakob R Izbicki; Daniel Perez; Andreas Marx Journal: Dis Markers Date: 2019-12-23 Impact factor: 3.434