Gissou Azabdaftari1, S Nahum Goldberg, Helen H Wang. 1. Departnent of Pathology, University of Colorado at Denver Health Sciences Center, Aurora, Colorado, USA. gissou.azabdaftari@roswellpark.org
Abstract
OBJECTIVE: To assess the value of on-site specimen adequacy evaluations. STUDY DESIGN: We reviewed reports of 144 image-guided fine and/or core needle biopsies from kidney, liver, lung, pancreas and retroperitoneum. One hundred nine (76%) had on-site evaluations performed, and 35 (24%) specimens did not receive any evaluation at the time of the procedure. Followup information up to 30 months was obtained on 131 (91%) to determine the nature of the lesion. RESULTS: For procedures involving lung, radiologists requested on-site evaluations for 93% of their procedures, while pulmonologists did not request on-site evaluations during the study period but obtained both fine needle aspirates and cores in 76% of their procedures. Radiologists were much more likely to obtain a definitive positive diagnosis for lesions that were confirmed to be malignant than pulmonologists were (20/23 [87%] vs. 5/11 [45%], p = 0.03). CONCLUSION: On-site evaluations improved the percentage of definitive "positive" diagnoses of the malignant lesions on cytology from 33% (5/15) to 74% (53/72) (p = 0.003). On-site evaluation did not have any effect on the diagnostic yield of the lesions that were determined to be benign on followup (p = 0.54).
OBJECTIVE: To assess the value of on-site specimen adequacy evaluations. STUDY DESIGN: We reviewed reports of 144 image-guided fine and/or core needle biopsies from kidney, liver, lung, pancreas and retroperitoneum. One hundred nine (76%) had on-site evaluations performed, and 35 (24%) specimens did not receive any evaluation at the time of the procedure. Followup information up to 30 months was obtained on 131 (91%) to determine the nature of the lesion. RESULTS: For procedures involving lung, radiologists requested on-site evaluations for 93% of their procedures, while pulmonologists did not request on-site evaluations during the study period but obtained both fine needle aspirates and cores in 76% of their procedures. Radiologists were much more likely to obtain a definitive positive diagnosis for lesions that were confirmed to be malignant than pulmonologists were (20/23 [87%] vs. 5/11 [45%], p = 0.03). CONCLUSION: On-site evaluations improved the percentage of definitive "positive" diagnoses of the malignant lesions on cytology from 33% (5/15) to 74% (53/72) (p = 0.003). On-site evaluation did not have any effect on the diagnostic yield of the lesions that were determined to be benign on followup (p = 0.54).
Authors: Louise M Fanchon; Snjezana Dogan; Andre L Moreira; Sean A Carlin; C Ross Schmidtlein; Ellen Yorke; Aditya P Apte; Irene A Burger; Jeremy C Durack; Joseph P Erinjeri; Majid Maybody; Heiko Schöder; Robert H Siegelbaum; Constantinos T Sofocleous; Joseph O Deasy; Stephen B Solomon; John L Humm; Assen S Kirov Journal: J Nucl Med Date: 2015-02-26 Impact factor: 10.057
Authors: Assen S Kirov; Louise M Fanchon; Daniel Seiter; Christian Czmielewski; James Russell; Snjezana Dogan; Sean Carlin; Katja Pinker-Domenig; Ellen Yorke; C Ross Schmidtlein; Vitaly Boyko; Sho Fujisawa; Katia Manova-Todorova; Pat Zanzonico; Lawrence Dauer; Joseph O Deasy; John L Humm; Stephen Solomon Journal: Med Phys Date: 2018-03-23 Impact factor: 4.071
Authors: Florian J Fintelmann; Fabian M Troschel; Martin W Kuklinski; Shaunagh McDermott; Milena Petranovic; Subba R Digumarthy; Amita Sharma; Amelie S Troschel; Melissa C Price; Lida P Hariri; Matthew D Gilman; Joanne O Shepard; Lecia V Sequist; Zofia Piotrowska Journal: Oncologist Date: 2019-05-31