Literature DB >> 20391556

Identification of tri- and tetracyclic pyrimidinediones as sirtuin inhibitors.

Dante Rotili1, Domenico Tarantino, Vincenzo Carafa, Ester Lara, Sarah Meade, Giorgia Botta, Angela Nebbioso, Jörg Schemies, Manfred Jung, Aleksey G Kazantsev, Manel Esteller, Mario F Fraga, Lucia Altucci, Antonello Mai.   

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Year:  2010        PMID： 20391556     DOI： 10.1002/cmdc.201000030

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


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  14 in total

1.  The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation.

Authors:  Teresa Faria Pais; Éva M Szegő; Oldriska Marques; Leonor Miller-Fleming; Pedro Antas; Patrícia Guerreiro; Rita Machado de Oliveira; Burcu Kasapoglu; Tiago Fleming Outeiro
Journal:  EMBO J       Date:  2013-09-06       Impact factor: 11.598

Review 2.  SIRT1 and Neural Cell Fate Determination.

Authors:  Yulong Cai; Le Xu; Haiwei Xu; Xiaotang Fan
Journal:  Mol Neurobiol       Date:  2015-04-08       Impact factor: 5.590

Review 3.  Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs.

Authors:  Khaled M Elattar; Ayman Y El-Khateeb; Sahar E Hamed
Journal:  RSC Med Chem       Date:  2022-05-06

Review 4.  Sirtuin modulators: past, present, and future perspectives.

Authors:  Francesco Fiorentino; Nicola Mautone; Martina Menna; Francesca D'Acunzo; Antonello Mai; Dante Rotili
Journal:  Future Med Chem       Date:  2022-05-18       Impact factor: 4.767

Review 5.  Small molecule SIRT1 activators for the treatment of aging and age-related diseases.

Authors:  Basil P Hubbard; David A Sinclair
Journal:  Trends Pharmacol Sci       Date:  2014-01-16       Impact factor: 14.819

Review 6.  Sirtuin inhibitors as anticancer agents.

Authors:  Jing Hu; Hui Jing; Hening Lin
Journal:  Future Med Chem       Date:  2014-05       Impact factor: 3.808

Review 7.  Biological and catalytic functions of sirtuin 6 as targets for small-molecule modulators.

Authors:  Mark A Klein; John M Denu
Journal:  J Biol Chem       Date:  2020-06-09       Impact factor: 5.157

8.  Identification of specific and semi-specific SIRT inhibitors through computer-aided studies.

Authors:  Antonello Mai
Journal:  Aging (Albany NY)       Date:  2011-09       Impact factor: 5.682

9.  Structure-based development of novel sirtuin inhibitors.

Authors:  Christine Schlicker; Gina Boanca; Mahadevan Lakshminarasimhan; Clemens Steegborn
Journal:  Aging (Albany NY)       Date:  2011-09       Impact factor: 5.682

Review 10.  Sirtuin functions and modulation: from chemistry to the clinic.

Authors:  Vincenzo Carafa; Dante Rotili; Mariantonietta Forgione; Francesca Cuomo; Enrica Serretiello; Gebremedhin Solomon Hailu; Elina Jarho; Maija Lahtela-Kakkonen; Antonello Mai; Lucia Altucci
Journal:  Clin Epigenetics       Date:  2016-05-25       Impact factor: 6.551
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