Literature DB >> 20391196

Synthesis of beta-hydroxyphosphonate and 1,2-dihydroxy acyclic nucleoside analogs via 1,3-dipolar cycloaddition strategy.

M Ganesan1, K M Muraleedharan.   

Abstract

A convenient synthetic approach toward nucleoside analogs where beta-hydroxyphosphonate- or 1,2-dihydroxy units are connected to the nucleic acid base through a triazole spacer is discussed.

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Year:  2010        PMID： 20391196     DOI： 10.1080/15257771003597709

Source DB:  PubMed          Journal:  Nucleosides Nucleotides Nucleic Acids        ISSN： 1525-7770            Impact factor:   1.381


  6 in total

1.  Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.

Authors:  Keith Clinch; Douglas R Crump; Gary B Evans; Keith Z Hazleton; Jennifer M Mason; Vern L Schramm; Peter C Tyler
Journal:  Bioorg Med Chem       Date:  2013-03-05       Impact factor: 3.641

2.  Design, synthesis, antiviral and cytostatic activity of ω-(1H-1,2,3-triazol-1-yl)(polyhydroxy)alkylphosphonates as acyclic nucleotide analogues.

Authors:  Iwona E Głowacka; Jan Balzarini; Graciela Andrei; Robert Snoeck; Dominique Schols; Dorota G Piotrowska
Journal:  Bioorg Med Chem       Date:  2014-05-20       Impact factor: 3.641

3.  Multicomponent click synthesis of new 1,2,3-triazole derivatives of pyrimidine nucleobases: promising acidic corrosion inhibitors for steel.

Authors:  Rodrigo González-Olvera; Araceli Espinoza-Vázquez; Guillermo E Negrón-Silva; Manuel E Palomar-Pardavé; Mario A Romero-Romo; Rosa Santillan
Journal:  Molecules       Date:  2013-12-06       Impact factor: 4.411

Review 4.  Chemical architecture and applications of nucleic acid derivatives containing 1,2,3-triazole functionalities synthesized via click chemistry.

Authors:  Tim Efthymiou; Wei Gong; Jean-Paul Desaulniers
Journal:  Molecules       Date:  2012-10-26       Impact factor: 4.411

5.  Design, Synthesis, and the Biological Evaluation of a New Series of Acyclic 1,2,3-Triazole Nucleosides.

Authors:  Iwona E Głowacka; Graciela Andrei; Dominique Schols; Robert Snoeck; Katarzyna Gawron
Journal:  Arch Pharm (Weinheim)       Date:  2017-08-01       Impact factor: 3.751

6.  The synthesis, antiviral, cytostatic and cytotoxic evaluation of a new series of acyclonucleotide analogues with a 1,2,3-triazole linker.

Authors:  Iwona E Głowacka; Jan Balzarini; Andrzej E Wróblewski
Journal:  Eur J Med Chem       Date:  2013-10-30       Impact factor: 6.514
  6 in total

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