Literature DB >> 20390741

Synthesis and antitumor activity of bisindolylmaleimide and amino acid ester conjugates.

Ke Wang1, Xiang-Yan Li, Xiao-Guang Chen, Zhan-Zhu Liu.   

Abstract

A series of novel bisindolylmaleimide and natural amino acid ester conjugates were synthesized and evaluated for their inhibitory activity against six tumor cell lines. Some compounds displayed interesting cytotoxic profiles. The most active compound 8e showed inhibitory activity against several human cancer cell lines.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20390741     DOI: 10.1080/10286020903413385

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  1 in total

1.  Bisindolylmaleimide alkaloid BMA-155Cl induces autophagy and apoptosis in human hepatocarcinoma HepG-2 cells through the NF-κB p65 pathway.

Authors:  Xiao Sun; Lin Li; Hong-Guang Ma; Pu Sun; Qi-Lin Wang; Ting-Ting Zhang; Yue-Mao Shen; Wei-Ming Zhu; Xia Li
Journal:  Acta Pharmacol Sin       Date:  2017-03-06       Impact factor: 6.150

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.