Literature DB >> 20388165

Erectile function rehabilitation in the radical prostatectomy patient.

John P Mulhall1, Anthony J Bella, Alberto Briganti, Andrew McCullough, Gerald Brock.   

Abstract

INTRODUCTION: Prostate cancer is common and is being diagnosed in younger men now compared with two decades ago. Long-term functional outcomes are of significant importance to patient and impact upon the patient decision-making process regarding choice of therapy. Erectile function preservation (rehabilitation) has gained significant traction worldwide despite the absence of definitive evidence in its favor. AIM: To define the role of rehabilitation in the prostate cancer patient who has undergone radical prostatectomy (RP).
METHODS: A committee of five experts in the field from three countries was convened, and using a thorough analysis of the literature and the Delphi approach to expert opinion, recommendations were arrived at for clinicians treating men with prostate cancer before and after definitive surgical management.
RESULTS: Recommendations arrived at included: that clinicians should discuss prevalence rates, the pathophysiology of erectile dysfunction after RP and the predictors of erectile function recovery, that validated instruments should be used using the published cut-offs for normalcy, that rehabilitation be discussed with patients, and that they be informed that significant potential benefits may be associated with rehabilitation.
CONCLUSIONS: The International Consensus of Sexual Medicine (ICSM) 2001 committee on rehabilitation after radical prostatectomy recommended that a discussion occur regarding rehabilitation in all patients undergoing or who have undergone RP. However, the committee recognized the absence of definitive data to date and could not comment on the optimal approach to rehabilitation at this time.

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Year:  2010        PMID: 20388165     DOI: 10.1111/j.1743-6109.2010.01804.x

Source DB:  PubMed          Journal:  J Sex Med        ISSN: 1743-6095            Impact factor:   3.802


  36 in total

1.  Cavernous nerve repair with allogenic adipose matrix and autologous adipose-derived stem cells.

Authors:  Guiting Lin; Maarten Albersen; Ahmed M Harraz; Thomas M Fandel; Maurice Garcia; Mary H McGrath; Badrinath R Konety; Tom F Lue; Ching-Shwun Lin
Journal:  Urology       Date:  2011-04-13       Impact factor: 2.649

Review 2.  Focusing on sexual rehabilitation besides penile rehabilitation following radical prostatectomy is important.

Authors:  Daphné Vanderhaeghe; Maarten Albersen; Emmanuel Weyne
Journal:  Int J Impot Res       Date:  2021-03-22       Impact factor: 2.896

Review 3.  Psychosocial perspectives on sexual recovery after prostate cancer treatment.

Authors:  Lauren M Walker; Richard J Wassersug; John W Robinson
Journal:  Nat Rev Urol       Date:  2015-03-10       Impact factor: 14.432

Review 4.  Treatment options for localized prostate cancer.

Authors:  Mira Keyes; Juanita Crook; Gerard Morton; Eric Vigneault; Nawaid Usmani; W James Morris
Journal:  Can Fam Physician       Date:  2013-12       Impact factor: 3.275

5.  Effects of intracavernous injection of adipose-derived stem cells on cavernous nerve regeneration in a rat model.

Authors:  Chengcheng Ying; Mei Yang; Xinmin Zheng; Wanli Hu; Xinghuan Wang
Journal:  Cell Mol Neurobiol       Date:  2012-11-17       Impact factor: 5.046

Review 6.  Racial Disparities in Sexual Dysfunction Outcomes After Prostate Cancer Treatment: Myth or Reality?

Authors:  Arthur L Burnett
Journal:  J Racial Ethn Health Disparities       Date:  2015-05-28

Review 7.  Erectile dysfunction after radical prostatectomy: treatment options.

Authors:  Sidney Glina
Journal:  Drugs Aging       Date:  2011-04-01       Impact factor: 3.923

8.  Adipose tissue-derived stem cells secrete CXCL5 cytokine with neurotrophic effects on cavernous nerve regeneration.

Authors:  Haiyang Zhang; Rong Yang; Zhong Wang; Guiting Lin; Tom F Lue; Ching-Shwun Lin
Journal:  J Sex Med       Date:  2010-11-29       Impact factor: 3.802

Review 9.  Stem cell therapy for erectile dysfunction: a critical review.

Authors:  Ching-Shwun Lin; Zhong-Cheng Xin; Zhong Wang; Chunhua Deng; Yun-Ching Huang; Guiting Lin; Tom F Lue
Journal:  Stem Cells Dev       Date:  2011-09-07       Impact factor: 3.272

10.  The Prostate Cancer Rehabilitation Clinic: a biopsychosocial clinic for sexual dysfunction after radical prostatectomy.

Authors:  A Matthew; N Lutzky-Cohen; L Jamnicky; K Currie; A Gentile; D Santa Mina; N Fleshner; A Finelli; R Hamilton; G Kulkarni; M Jewett; A Zlotta; J Trachtenberg; Z Yang; D Elterman
Journal:  Curr Oncol       Date:  2018-12-01       Impact factor: 3.677

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