| Literature DB >> 20387794 |
John D Bauer1, Ryan W King, Sean F Brady.
Abstract
Two new azaquinones, utahmycins A (1) and B (2), were isolated from cultures of Streptomyces albus J1704 transformed with the environmental DNA-derived Erd gene cluster. The structures of 1 and 2 were elucidated by spectroscopic analyses. The structure of 1 was confirmed by single-crystal X-ray diffraction analysis. Both metabolites appear to arise from the addition of a nitrogen atom to erdacin biosynthetic intermediates. Utahmycin A (1) is the first example of a biologically derived 1,3-dimethyl-2-azaanthraquinone.Entities:
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Year: 2010 PMID： 20387794 PMCID： PMC2893554 DOI： 10.1021/np900786s
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050