Literature DB >> 20386812

Silver catalyzed cascade synthesis of alkaloid ring systems: concise total synthesis of fascaplysin, homofascaplysin C and analogues.

Herbert Waldmann1, Luc Eberhardt, Kathrin Wittstein, Kamal Kumar.   

Abstract

A silver catalyzed and microwave assisted one-pot cascade synthesis provides efficient access to diverse alkaloid-inspired scaffold classes, and a concise and efficient total synthesis of homofascaplysin C and fascaplysin.

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Year:  2010        PMID： 20386812     DOI： 10.1039/c001350a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  5 in total

1.  Total Syntheses and Preliminary Biological Evaluation of Brominated Fascaplysin and Reticulatine Alkaloids and Their Analogues.

Authors:  Maxim E Zhidkov; Polina A Smirnova; Oleg A Tryapkin; Alexey V Kantemirov; Yuliya V Khudyakova; Olesya S Malyarenko; Svetlana P Ermakova; Valeria P Grigorchuk; Moritz Kaune; Gunhild von Amsberg; Sergey A Dyshlovoy
Journal:  Mar Drugs       Date:  2019-08-25       Impact factor: 5.118

Review 2.  Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria.

Authors:  Andre G Tempone; Pauline Pieper; Samanta E T Borborema; Fernanda Thevenard; Joao Henrique G Lago; Simon L Croft; Edward A Anderson
Journal:  Nat Prod Rep       Date:  2021-12-15       Impact factor: 13.423

3.  A pyrone remodeling strategy to access diverse heterocycles: application to the synthesis of fascaplysin natural products.

Authors:  Vignesh Palani; Melecio A Perea; Kristen E Gardner; Richmond Sarpong
Journal:  Chem Sci       Date:  2020-11-27       Impact factor: 9.825

4.  'One-pot' synthesis of dihydrobenzo[4,5][1,3]oxazino[2,3-a] isoquinolines via a silver(I)-catalyzed cascade approach.

Authors:  Baifeng Jiang; Yu Zhou; Qingya Kong; Hualiang Jiang; Hong Liu; Jian Li
Journal:  Molecules       Date:  2013-01-11       Impact factor: 4.411

5.  Study of Structure-Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents.

Authors:  Maxim E Zhidkov; Moritz Kaune; Alexey V Kantemirov; Polina A Smirnova; Pavel V Spirin; Maria A Sidorova; Sergey A Stadnik; Elena Y Shyrokova; Dmitry N Kaluzhny; Oleg A Tryapkin; Tobias Busenbender; Jessica Hauschild; Tina Rohlfing; Vladimir S Prassolov; Carsten Bokemeyer; Markus Graefen; Gunhild von Amsberg; Sergey A Dyshlovoy
Journal:  Mar Drugs       Date:  2022-03-02       Impact factor: 5.118
  5 in total

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