Literature DB >> 20386676

Radon in indoor spaces: an underestimated risk factor for lung cancer in environmental medicine.

Klaus Schmid1, Torsten Kuwert, Hans Drexler.   

Abstract

BACKGROUND: Occupational medicine has long recognized radon to be a cause of lung cancer, especially among miners working under ground. Until recently, however, little scientific evidence was available about the risk to the general population caused by indoor radon.
METHODS: The authors analyzed literature that they found by a selective search in the light of the recently published S1 guideline of the German Society of Occupational and Environmental Medicine (Deutsche Gesellschaft für Arbeitsmedizin und Umweltmedizin) and a recent publication of the German Commission on Radiological Protection (Strahlenschutzkommission).
RESULTS: Exposure to indoor radon and its decay products is a major contributor to the radiation exposure of the general population. In Germany, the mean radiation exposure due to radon in living rooms and bedrooms is about 49 Bq/m(3). It is well documented in the scientific literature that indoor radon significantly increases the risk of lung cancer, probably in a linear dose-response relationship with no threshold. Every 100 Bq/m(3) increase in the radon concentration is estimated to increase the relative risk for lung cancer by 8% to 16%. After cigarette smoking, radon is the second main cause of lung cancer in the general population without occupational exposure.
CONCLUSIONS: From the point of view of preventive environmental medicine, it is important to identify buildings with high radon concentrations, initiate appropriate measures, and minimize radon exposure, particularly in new buildings.

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Year:  2010        PMID: 20386676      PMCID: PMC2853156          DOI: 10.3238/arztebl.2010.0181

Source DB:  PubMed          Journal:  Dtsch Arztebl Int        ISSN: 1866-0452            Impact factor:   5.594


  24 in total

1.  Exposure to residential radon causes lung cancer. For the proposition.

Authors:  R William Field
Journal:  Med Phys       Date:  2003-04       Impact factor: 4.071

2.  Indoor radon and lung cancer risk in connecticut and utah.

Authors:  Dale P Sandler; Clarice R Weinberg; David L Shore; Victor E Archer; Mary Bishop Stone; Joseph L Lyon; Lynne Rothney-Kozlak; Marsha Shepherd; Jan A J Stolwijk
Journal:  J Toxicol Environ Health A       Date:  2006-04

3.  World Health Organization's International Radon Project.

Authors:  Jan M Zielinski; Zhanat Carr; Daniel Krewski; Michael Repacholi
Journal:  J Toxicol Environ Health A       Date:  2006-04

4.  Prediction of 222Rn in Danish dwellings using geology and house construction information from central databases.

Authors:  Claus E Andersen; Ole Raaschou-Nielsen; Helle Primdal Andersen; Morten Lind; Peter Gravesen; Birthe L Thomsen; Kaare Ulbak
Journal:  Radiat Prot Dosimetry       Date:  2006-07-25       Impact factor: 0.972

5.  Case-control study of lung cancer risk from residential radon exposure in Worcester county, Massachusetts.

Authors:  Richard E Thompson; Donald F Nelson; Joel H Popkin; Zenaida Popkin
Journal:  Health Phys       Date:  2008-03       Impact factor: 1.316

6.  Protection against radon-222 at home and at work. A report of a task group of the International Commission on Radiological Protection.

Authors: 
Journal:  Ann ICRP       Date:  1993

7.  Lung cancer risk from residential radon: meta-analysis of eight epidemiologic studies.

Authors:  J H Lubin; J D Boice
Journal:  J Natl Cancer Inst       Date:  1997-01-01       Impact factor: 13.506

8.  Risk of lung cancer and residential radon in China: pooled results of two studies.

Authors:  Jay H Lubin; Zuo Yuan Wang; John D Boice; Zhao Yi Xu; William J Blot; Long De Wang; Ruth A Kleinerman
Journal:  Int J Cancer       Date:  2004-03       Impact factor: 7.396

9.  Population attributable fraction for lung cancer due to residential radon in Switzerland and Germany.

Authors:  Susanne Menzler; Georges Piller; Martha Gruson; Angelika Schaffrath Rosario; H-Erich Wichmann; Lothar Kreienbrock
Journal:  Health Phys       Date:  2008-08       Impact factor: 1.316

10.  Lung cancer deaths from indoor radon and the cost effectiveness and potential of policies to reduce them.

Authors:  Alastair Gray; Simon Read; Paul McGale; Sarah Darby
Journal:  BMJ       Date:  2009-01-06
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  13 in total

1.  Correspondence (letter to the editor): Creating awareness.

Authors:  Ferid Shannoun
Journal:  Dtsch Arztebl Int       Date:  2010-10-15       Impact factor: 5.594

2.  Correspondence (letter to the editor): Risk associated with radon is overestimated.

Authors:  Ernst Eising
Journal:  Dtsch Arztebl Int       Date:  2010-10-15       Impact factor: 5.594

3.  Correspondence (letter to the editor): Radon in drinking water.

Authors:  Hermann Dertinger; Konrad Andrassy
Journal:  Dtsch Arztebl Int       Date:  2010-10-15       Impact factor: 5.594

4.  Correspondence (letter to the editor): Radon balneology.

Authors:  Helmut Schlarb
Journal:  Dtsch Arztebl Int       Date:  2010-10-15       Impact factor: 5.594

5.  Regional deprivation in Bavaria, Germany: linking a new deprivation score with registry data for lung and colorectal cancer.

Authors:  Laura Kuznetsov; Werner Maier; Matthias Hunger; Martin Meyer; Andreas Mielck
Journal:  Int J Public Health       Date:  2012-10       Impact factor: 3.380

6.  Cancers Due to Infection and Selected Environmental Factors.

Authors:  Thomas Gredner; Gundula Behrens; Christian Stock; Hermann Brenner; Ute Mons
Journal:  Dtsch Arztebl Int       Date:  2018-09-03       Impact factor: 5.594

Review 7.  Lung cancer in never smokers.

Authors:  Ping Yang
Journal:  Semin Respir Crit Care Med       Date:  2011-04-15       Impact factor: 3.119

8.  Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.

Authors:  Xin Cai; Jianhui Sheng; Chuanning Tang; Vijayalakshmi Nandakumar; Hua Ye; Hong Ji; Haiying Tang; Yu Qin; Hongwei Guan; Feng Lou; Dandan Zhang; Hong Sun; Haichao Dong; Guangchun Zhang; Zhiyuan Liu; Zhishou Dong; Baishuai Guo; He Yan; Chaowei Yan; Lu Wang; Ziyi Su; Yangyang Li; Lindsey Jones; Xue F Huang; Si-Yi Chen; Taihua Wu; Hongli Lin
Journal:  PLoS One       Date:  2014-04-23       Impact factor: 3.240

9.  Identification of Genetic Mutations in Human Lung Cancer by Targeted Sequencing.

Authors:  Hongxiang Feng; Xiaowei Wang; Zhenrong Zhang; Chuanning Tang; Hua Ye; Lindsey Jones; Feng Lou; Dandan Zhang; Shouwen Jiang; Hong Sun; Haichao Dong; Guangchun Zhang; Zhiyuan Liu; Zhishou Dong; Baishuai Guo; He Yan; Chaowei Yan; Lu Wang; Ziyi Su; Yangyang Li; Vijayalakshmi Nandakumar; Xue F Huang; Si-Yi Chen; Deruo Liu
Journal:  Cancer Inform       Date:  2015-06-29

10.  Children's Exposure to Radon in Nursery and Primary Schools.

Authors:  Pedro T B S Branco; Rafael A O Nunes; Maria C M Alvim-Ferraz; Fernando G Martins; Sofia I V Sousa
Journal:  Int J Environ Res Public Health       Date:  2016-03-30       Impact factor: 3.390

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