Literature DB >> 20385903

Connecting genes to brain in the autism spectrum disorders.

Brett S Abrahams1, Daniel H Geschwind.   

Abstract

The autism spectrum disorders (ASDs) are a complex group of neuropsychiatric conditions involving language, social communication, and mental flexibility. Here, we attempt to place recent genetic advances within a developmental and anatomical context. Recent progress in identifying ASD candidate genes supports involvement of multiple brain regions, including the frontal lobes, anterior temporal lobes, caudate, and cerebellum. Understanding genetic data within an anatomical context will be critical to explain how individual risk factors operate to shape phenotypic presentation in patients.

Entities:  

Mesh：

Year:  2010        PMID： 20385903      PMCID： PMC3645845          DOI： 10.1001/archneurol.2010.47

Source DB:  PubMed          Journal:  Arch Neurol        ISSN： 0003-9942


  46 in total

1.  Autism and the cerebellum: evidence from tuberous sclerosis.

Authors:  A M Weber; J C Egelhoff; J M McKellop; D N Franz
Journal:  J Autism Dev Disord       Date:  2000-12

2.  Abnormal ventral temporal cortical activity during face discrimination among individuals with autism and Asperger syndrome.

Authors:  R T Schultz; I Gauthier; A Klin; R K Fulbright; A W Anderson; F Volkmar; P Skudlarski; C Lacadie; D J Cohen; J C Gore
Journal:  Arch Gen Psychiatry       Date:  2000-04

3.  Monozygotic twins with tuberous sclerosis discordant for the severity of developmental deficits.

Authors:  Ayla Humphrey; J Nicholas P Higgins; John R W Yates; Patrick F Bolton
Journal:  Neurology       Date:  2004-03-09       Impact factor: 9.910

4.  Language-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds.

Authors:  S Carmen Panaitof; Brett S Abrahams; Hongmei Dong; Daniel H Geschwind; Stephanie A White
Journal:  J Comp Neurol       Date:  2010-06-01       Impact factor: 3.215

5.  Autism in tuberous sclerosis complex is related to both cortical and subcortical dysfunction.

Authors:  E Asano; D C Chugani; O Muzik; M Behen; J Janisse; R Rothermel; T J Mangner; P K Chakraborty; H T Chugani
Journal:  Neurology       Date:  2001-10-09       Impact factor: 9.910

6.  Minicolumnar pathology in autism.

Authors:  Manuel F Casanova; Daniel P Buxhoeveden; Andrew E Switala; Emil Roy
Journal:  Neurology       Date:  2002-02-12       Impact factor: 9.910

Review 7.  Structural and functional maturation of the developing primate brain.

Authors:  Pat Levitt
Journal:  J Pediatr       Date:  2003-10       Impact factor: 4.406

8.  Cortical sulcal maps in autism.

Authors:  Jennifer G Levitt; Rebecca E Blanton; Susan Smalley; P M Thompson; Donald Guthrie; James T McCracken; Tania Sadoun; Laura Heinichen; Arthur W Toga
Journal:  Cereb Cortex       Date:  2003-07       Impact factor: 5.357

9.  X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family.

Authors:  Frédéric Laumonnier; Frédérique Bonnet-Brilhault; Marie Gomot; Romuald Blanc; Albert David; Marie-Pierre Moizard; Martine Raynaud; Nathalie Ronce; Eric Lemonnier; Patrick Calvas; Béatrice Laudier; Jamel Chelly; Jean-Pierre Fryns; Hans-Hilger Ropers; Ben C J Hamel; Christian Andres; Catherine Barthélémy; Claude Moraine; Sylvain Briault
Journal:  Am J Hum Genet       Date:  2004-02-12       Impact factor: 11.025

Review 10.  Annotation: the neural basis of social impairments in autism: the role of the dorsal medial-frontal cortex and anterior cingulate system.

Authors:  Peter Mundy
Journal:  J Child Psychol Psychiatry       Date:  2003-09       Impact factor: 8.982
View more
  75 in total

Review 1.  Oxytocin receptor and Mecp2 308/Y knockout mice exhibit altered expression of autism-related social behaviors.

Authors:  Roger L H Pobbe; Brandon L Pearson; D Caroline Blanchard; Robert J Blanchard
Journal:  Physiol Behav       Date:  2012-03-03

2.  Brief report: life history and neuropathology of a gifted man with Asperger syndrome.

Authors:  Karen M Weidenheim; Alfonso Escobar; Isabelle Rapin
Journal:  J Autism Dev Disord       Date:  2012-03

Review 3.  Optogenetics enlightens neuroscience drug discovery.

Authors:  Chenchen Song; Thomas Knöpfel
Journal:  Nat Rev Drug Discov       Date:  2015-11-27       Impact factor: 84.694

4.  A comparison of pragmatic language in boys with autism and fragile X syndrome.

Authors:  Jessica Klusek; Gary E Martin; Molly Losh
Journal:  J Speech Lang Hear Res       Date:  2014-10       Impact factor: 2.297

Review 5.  Modeling autistic features in animals.

Authors:  Paul H Patterson
Journal:  Pediatr Res       Date:  2011-05       Impact factor: 3.756

6.  Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase.

Authors:  Shenfeng Qiu; Charles T Anderson; Pat Levitt; Gordon M G Shepherd
Journal:  J Neurosci       Date:  2011-04-13       Impact factor: 6.167

7.  Genetic insights beginning to divide autism diagnosis.

Authors:  Monica Heger
Journal:  Nat Med       Date:  2011-04       Impact factor: 53.440

8.  Modifier genes and non-genetic factors reshape anatomical deficits in Zfp423-deficient mice.

Authors:  Wendy A Alcaraz; Edward Chen; Phoebe Valdes; Eunnie Kim; Yuan Hung Lo; Jennifer Vo; Bruce A Hamilton
Journal:  Hum Mol Genet       Date:  2011-07-05       Impact factor: 6.150

9.  Neurofeedback training produces normalization in behavioural and electrophysiological measures of high-functioning autism.

Authors:  Jaime A Pineda; Karen Carrasco; Mike Datko; Steven Pillen; Matt Schalles
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2014-04-28       Impact factor: 6.237

10.  Abnormal glutamate release in aged BTBR mouse model of autism.

Authors:  Hongen Wei; Caiyun Ding; Guorong Jin; Haizhen Yin; Jianrong Liu; Fengyun Hu
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.