| Literature DB >> 20385357 |
Manuel Collado1, Manuel Serrano.
Abstract
ARF is a key activator of p53, and together they form a critical duo for protection against cancer. Previous evidence had recognized the regulatory potential of ubiquitin-mediated degradation of ARF. The recent identification of TRIP12/ULF as a ubiquitin ligase of ARF adds an important missing piece to the ARF/p53 pathway. Copyright 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID: 20385357 DOI: 10.1016/j.ccr.2010.03.015
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743