Literature DB >> 20385282

Redo surgery in Hirschsprung disease: what did we learn? Unicentric experience on 70 patients.

Alessio Pini-Prato1, Girolamo Mattioli, Camilla Giunta, Stefano Avanzini, Paolo Magillo, Giovanni Maria Bisio, Vincenzo Jasonni.   

Abstract

PURPOSE: This article is aimed at describing a series of 70 patients who underwent a redo pull-through in the period between January 1991 and January 2007 and to compare them with a series of consecutive patients with Hirschsprung disease who underwent a single pull-through.
METHODS: The notes were reviewed, and a comprehensive interview based on a disease-specific questionnaire for continence and quality of life was submitted to all eligible patients. We used a number of consecutive patients who underwent a single pull-through for Hirschsprung disease as control group.
RESULTS: Seventy patients were included. Residual aganglionosis in pulled-through bowel or retained aganglionic rectum represented the indications to reoperation in most cases. Intestinal obstruction represented the leading symptom in more than 60% of patients. We adopted either the endorectal pull-through, the Duhamel, or the Swenson procedure. Thirty-six patients were assessed for long-term outcome. One third experienced complications. Long-term continence was satisfactory in 70%. Enterocolitis, soiling, and perineal excoriations were complained by 30%. Excellent to good perspectives were described by 94%, and excellent to good cosmetic results by 22%. The only significant difference with control group (109 patients) involved cosmetic appearance, whereas soiling, although more frequent, could not be considered significantly increased.
CONCLUSIONS: Patients who experience failure of a pull-through must go through multiple procedures to achieve definitive results. Although overall outcome does not significantly differ from that of a single effective pull-through, great efforts should be made to minimize complications and avoid the need for a redo, which requires experienced surgeons and highly committed families for a longer course of the disease. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20385282     DOI: 10.1016/j.jpedsurg.2009.08.001

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  7 in total

Review 1.  Residual aganglionosis after pull-through operation for Hirschsprung's disease: a systematic review and meta-analysis.

Authors:  Florian Friedmacher; Prem Puri
Journal:  Pediatr Surg Int       Date:  2011-10       Impact factor: 1.827

2.  Re-operation for Hirschsprung's disease: experience in 24 patients from China.

Authors:  Qingfeng Sheng; Zhibao Lv; Xianmin Xiao
Journal:  Pediatr Surg Int       Date:  2012-02-23       Impact factor: 1.827

3.  Surgical approach and functional outcome of redo pull-through for postoperative complications in Hirschsprung's disease.

Authors:  Qi Li; Zhen Zhang; Ping Xiao; Ya Ma; Yuchun Yan; Qian Jiang; Yee Low; Long Li
Journal:  Pediatr Surg Int       Date:  2021-08-20       Impact factor: 1.827

Review 4.  Hirschsprung-associated enterocolitis: prevention and therapy.

Authors:  Philip K Frykman; Scott S Short
Journal:  Semin Pediatr Surg       Date:  2012-11       Impact factor: 2.754

Review 5.  Long-term results of transanal pull-through for Hirschsprung's disease: a meta-analysis.

Authors:  J Zimmer; C Tomuschat; P Puri
Journal:  Pediatr Surg Int       Date:  2016-07-06       Impact factor: 1.827

6.  Dynamic integration of enteric neural stem cells in ex vivo organotypic colon cultures.

Authors:  Georgina Navoly; Conor J McCann
Journal:  Sci Rep       Date:  2021-08-05       Impact factor: 4.379

7.  Redo pull-through in total colonic aganglionosis due to residual aganglionosis: a single center's experience.

Authors:  Jia-Yu Yan; Chun-Hui Peng; Wen-Bo Pang; Yong-Wei Chen; Cai-Ling Ding; Ya-Jun Chen
Journal:  Gastroenterol Rep (Oxf)       Date:  2020-12-07
  7 in total

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