Literature DB >> 20384250

Evaluation of delivered monitor unit accuracy of gated step-and-shoot IMRT using a two-dimensional detector array.

Kwang-Ho Cheong1, Sei-Kwon Kang, MeYeon Lee, Su Ssan Kim, SoAh Park, Tae-Jin Hwang, Kyoung Ju Kim, Do Hoon Oh, Hoonsik Bae, Tae-Suk Suh.   

Abstract

PURPOSE: To overcome the problem of organ motion in intensity-modulated radiation therapy (IMRT), gated IMRT is often used for the treatment of lung cancer. In this study, the authors investigated the accuracy of the delivered monitor units (MUs) from each segment during gated IMRT using a two-dimensional detector array for user-specific verification purpose.
METHODS: The authors planned a 6 MV photon, seven-port step-and-shoot lung IMRT delivery. The respiration signals for gated IMRT delivery were obtained from the one-dimensional moving phantom using the real-time position management (RPM) system (Varian Medical Systems, Palo Alto, CA). The beams were delivered using a Clinac iX (Varian Medical Systems, Palo Alto, CA) with the Millennium 120 MLC. The MatriXX (IBA Dosimetry GmbH, Germany) was validated through consistency and reproducibility tests as well as comparison with measurements from a Farmer-type ion chamber. The authors delivered beams with varying dose rates and duty cycles and analyzed the MatriXX data to evaluate MU delivery accuracy.
RESULTS: There was quite good agreement between the planned segment MUs and the MUs computed from the MatriXX within +/- 2% error. The beam-on times computed from the MatriXX data were almost identical for all cases, and they matched well with the RPM beam-on and beam-off signals. A slight difference was observed between them, but it was less than 40 ms. The gated IMRT delivery demonstrated an MU delivery accuracy that was equivalent to ungated IMRT, and the delivered MUs with a gating signal agreed with the planned MUs within +/- 0.5 MU regardless of dose rate and duty cycle.
CONCLUSIONS: The authors can conclude that gated IMRT is able to deliver an accurate dose to a patient during a procedure. The authors believe that the methodology and results can be transferred to other vendors' devices, particularly those that do not provide MLC log data for a verification purpose.

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Year:  2010        PMID: 20384250     DOI: 10.1118/1.3310806

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  2 in total

1.  Automatically gated image-guided breath-hold IMRT is a fast, precise, and dosimetrically robust treatment for lung cancer patients.

Authors:  Anna Simeonova-Chergou; Anika Jahnke; Kerstin Siebenlist; Florian Stieler; Sabine Mai; Judit Boda-Heggemann; Frederik Wenz; Frank Lohr; Lennart Jahnke
Journal:  Strahlenther Onkol       Date:  2016-01-15       Impact factor: 3.621

2.  Dosimetric evaluation of radiation dose rate effect in respiratory gated intensity modulated radiation therapy.

Authors:  C Khamfongkhruea; C Tannanonta; S Thongsawad
Journal:  Biomed Imaging Interv J       Date:  2012-01-01
  2 in total

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