BACKGROUND: Soft tissue liposarcomas are quite common in the adult population, whereas liposarcoma of the larynx is exceedingly rare. METHODS: We describe an exceptional case of liposarcoma of the posterior aspect of the left arytenoid in a 62-year-old woman who was treated with two endoscopic excisions and adjuvant radiotherapy (RT). This is the 32nd case of laryngeal liposarcoma reported in the English literature. RESULTS: After a 20 months follow-up, no local, regional recurrences or distant metastases were detected, and no functional complications are described for the patient. CONCLUSION: This case report highlights that endoscopic surgical treatment enables excellent organ and functional preservation. However, recurrence of laryngeal liposarcoma is the principal risk, so extended follow-up is essential. RT has no defined role in treatment but can be discussed, especially considering the surgical margins and recurrence status.
BACKGROUND: Soft tissue liposarcomas are quite common in the adult population, whereas liposarcoma of the larynx is exceedingly rare. METHODS: We describe an exceptional case of liposarcoma of the posterior aspect of the left arytenoid in a 62-year-old woman who was treated with two endoscopic excisions and adjuvant radiotherapy (RT). This is the 32nd case of laryngeal liposarcoma reported in the English literature. RESULTS: After a 20 months follow-up, no local, regional recurrences or distant metastases were detected, and no functional complications are described for the patient. CONCLUSION: This case report highlights that endoscopic surgical treatment enables excellent organ and functional preservation. However, recurrence of laryngeal liposarcoma is the principal risk, so extended follow-up is essential. RT has no defined role in treatment but can be discussed, especially considering the surgical margins and recurrence status.
Authors: M Van Glabbeke; A T van Oosterom; J W Oosterhuis; H Mouridsen; D Crowther; R Somers; J Verweij; A Santoro; J Buesa; T Tursz Journal: J Clin Oncol Date: 1999-01 Impact factor: 44.544
Authors: Fritz C Eilber; Frederick R Eilber; Jeffery Eckardt; Gerald Rosen; Elyn Riedel; Robert G Maki; Murray F Brennan; Samuel Singer Journal: Ann Surg Date: 2004-10 Impact factor: 12.969
Authors: Erica C Davis; Matthew T Ballo; Mario A Luna; Shreyakumar R Patel; Dianna B Roberts; Xiaolin Nong; Erich M Sturgis Journal: Head Neck Date: 2009-01 Impact factor: 3.147
Authors: Karen Fritchie; Toshi Ghosh; Rondell P Graham; Anja C Roden; David Schembri-Wismayer; Andrew Folpe; Michael Rivera Journal: Head Neck Pathol Date: 2020-05-14