BACKGROUND: Self-rated health predicts outcome in chronic disease, but such information is scarce in COPD. We aimed to assess self-rated health as an outcome predictor in carefully characterized patients with this condition. METHODS: This was a prospective study in 127 clinically stable patients with COPD (64 +/- 8 years, 79% men, 82% Global Initiative for Chronic Obstructive Lung Disease stage II or III). Self-rated health was assessed using a 5-grade Likert scale ranging from very poor to very good. RESULTS: During 26.0 +/- 4.9 months of follow-up, 78 patients experienced acute exacerbation, 39 were hospitalized, and 10 died. Poor or very poor self-rated health was reported by 19 patients (15%) and was more common in patients experiencing acute exacerbations (20% vs 6%, P = .027) and hospitalizations (19% vs 5%, P = .039). Kaplan-Meier curves demonstrated more acute exacerbations (P = .003) and hospitalizations (P = .008) in patients with poor or very poor self-rated health. In a fully adjusted Cox model of proportional hazard, poor or very poor self-rated health remained predictive of acute exacerbations (hazard ratio [HR], 1.80; 95% CI, 1.03-3.11) and hospitalizations (HR, 1.93; 95% CI, 1.12-3.68) but not of death. CONCLUSIONS: This study suggests that self-rated health is predictive of acute exacerbations and hospitalizations. Although prediction of mortality was limited, the study is supportive of self-rated health testing in COPD.
BACKGROUND: Self-rated health predicts outcome in chronic disease, but such information is scarce in COPD. We aimed to assess self-rated health as an outcome predictor in carefully characterized patients with this condition. METHODS: This was a prospective study in 127 clinically stable patients with COPD (64 +/- 8 years, 79% men, 82% Global Initiative for Chronic Obstructive Lung Disease stage II or III). Self-rated health was assessed using a 5-grade Likert scale ranging from very poor to very good. RESULTS: During 26.0 +/- 4.9 months of follow-up, 78 patients experienced acute exacerbation, 39 were hospitalized, and 10 died. Poor or very poor self-rated health was reported by 19 patients (15%) and was more common in patients experiencing acute exacerbations (20% vs 6%, P = .027) and hospitalizations (19% vs 5%, P = .039). Kaplan-Meier curves demonstrated more acute exacerbations (P = .003) and hospitalizations (P = .008) in patients with poor or very poor self-rated health. In a fully adjusted Cox model of proportional hazard, poor or very poor self-rated health remained predictive of acute exacerbations (hazard ratio [HR], 1.80; 95% CI, 1.03-3.11) and hospitalizations (HR, 1.93; 95% CI, 1.12-3.68) but not of death. CONCLUSIONS: This study suggests that self-rated health is predictive of acute exacerbations and hospitalizations. Although prediction of mortality was limited, the study is supportive of self-rated health testing in COPD.
Authors: Mitja Lainscak; Stephan von Haehling; Wolfram Doehner; Irena Sarc; Tina Jeric; Kristina Ziherl; Mitja Kosnik; Stefan D Anker; Stanislav Suskovic Journal: J Cachexia Sarcopenia Muscle Date: 2011-03-01 Impact factor: 12.910
Authors: Renata Ferrari; Suzana E Tanni; Laura M O Caram; Cristiane R Naves; Irma Godoy Journal: Health Qual Life Outcomes Date: 2011-12-09 Impact factor: 3.186
Authors: Marie-Josée Fleury; André Ngamini Ngui; Jean-Marie Bamvita; Guy Grenier; Jean Caron Journal: Int J Environ Res Public Health Date: 2014-10-15 Impact factor: 3.390
Authors: Piotr Kuna; Yavor Ivanov; Vasily Ivanovich Trofimov; Takefumi Saito; Ola Beckman; Thomas Bengtsson; Carin Jorup; François Maltais Journal: Respir Res Date: 2013-06-03
Authors: Nayara Tamayo-Fonseca; Andreu Nolasco; Jose A Quesada; Pamela Pereyra-Zamora; Inmaculada Melchor; Joaquin Moncho; Julia Calabuig; Carmen Barona Journal: BMC Health Serv Res Date: 2015-11-04 Impact factor: 2.655