| Literature DB >> 20382064 |
Abstract
Approximately 50,000 cases of superficial bladder cancer are diagnosed annually in the United States. Immunotherapy utilizing intravesical BCG is the most effective standard therapy for superficial transitional cell carcinoma of the bladder. Based on ease of administration, limited systemic dissemination, and the demonstrated activity of immunotherapy, superficial bladder cancer is an excellent target for virus based gene and immunotherapy. Thus far, clinical trials of virus therapy for bladder cancer have yielded mixed results. In this paper the results of several virus based clinical trials for bladder cancer are reviewed. 2010 Elsevier Ltd. All rights reserved.Entities:
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Year: 2010 PMID: 20382064 DOI: 10.1016/j.cytogfr.2010.02.003
Source DB: PubMed Journal: Cytokine Growth Factor Rev ISSN: 1359-6101 Impact factor: 7.638