Literature DB >> 20378609

Incomplete and noisy network data as a percolation process.

Michael P H Stumpf1, Carsten Wiuf.   

Abstract

We discuss the ramifications of noisy and incomplete observations of network data on the existence of a giant connected component (GCC). The existence of a GCC in a random graph can be described in terms of a percolation process, and building on general results for classes of random graphs with specified degree distributions we derive percolation thresholds above which GCCs exist. We show that sampling and noise can have a profound effect on the perceived existence of a GCC and find that both processes can destroy it. We also show that the absence of a GCC puts a theoretical upper bound on the false-positive rate and relate our percolation analysis to experimental protein-protein interaction data.

Mesh:

Year:  2010        PMID: 20378609      PMCID: PMC2935600          DOI: 10.1098/rsif.2010.0044

Source DB:  PubMed          Journal:  J R Soc Interface        ISSN: 1742-5662            Impact factor:   4.118


  32 in total

1.  Emergence of scaling in random networks

Authors: 
Journal:  Science       Date:  1999-10-15       Impact factor: 47.728

2.  Subnets of scale-free networks are not scale-free: sampling properties of networks.

Authors:  Michael P H Stumpf; Carsten Wiuf; Robert M May
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-14       Impact factor: 11.205

3.  Towards a proteome-scale map of the human protein-protein interaction network.

Authors:  Jean-François Rual; Kavitha Venkatesan; Tong Hao; Tomoko Hirozane-Kishikawa; Amélie Dricot; Ning Li; Gabriel F Berriz; Francis D Gibbons; Matija Dreze; Nono Ayivi-Guedehoussou; Niels Klitgord; Christophe Simon; Mike Boxem; Stuart Milstein; Jennifer Rosenberg; Debra S Goldberg; Lan V Zhang; Sharyl L Wong; Giovanni Franklin; Siming Li; Joanna S Albala; Janghoo Lim; Carlene Fraughton; Estelle Llamosas; Sebiha Cevik; Camille Bex; Philippe Lamesch; Robert S Sikorski; Jean Vandenhaute; Huda Y Zoghbi; Alex Smolyar; Stephanie Bosak; Reynaldo Sequerra; Lynn Doucette-Stamm; Michael E Cusick; David E Hill; Frederick P Roth; Marc Vidal
Journal:  Nature       Date:  2005-09-28       Impact factor: 49.962

4.  Some protein interaction data do not exhibit power law statistics.

Authors:  Reiko Tanaka; Tau-Mu Yi; John Doyle
Journal:  FEBS Lett       Date:  2005-09-26       Impact factor: 4.124

5.  How scale-free are biological networks.

Authors:  Raya Khanin; Ernst Wit
Journal:  J Comput Biol       Date:  2006-04       Impact factor: 1.479

6.  Functional organization of the yeast proteome by systematic analysis of protein complexes.

Authors:  Anne-Claude Gavin; Markus Bösche; Roland Krause; Paola Grandi; Martina Marzioch; Andreas Bauer; Jörg Schultz; Jens M Rick; Anne-Marie Michon; Cristina-Maria Cruciat; Marita Remor; Christian Höfert; Malgorzata Schelder; Miro Brajenovic; Heinz Ruffner; Alejandro Merino; Karin Klein; Manuela Hudak; David Dickson; Tatjana Rudi; Volker Gnau; Angela Bauch; Sonja Bastuck; Bettina Huhse; Christina Leutwein; Marie-Anne Heurtier; Richard R Copley; Angela Edelmann; Erich Querfurth; Vladimir Rybin; Gerard Drewes; Manfred Raida; Tewis Bouwmeester; Peer Bork; Bertrand Seraphin; Bernhard Kuster; Gitte Neubauer; Giulio Superti-Furga
Journal:  Nature       Date:  2002-01-10       Impact factor: 49.962

7.  A comprehensive two-hybrid analysis to explore the yeast protein interactome.

Authors:  T Ito; T Chiba; R Ozawa; M Yoshida; M Hattori; Y Sakaki
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

8.  Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.

Authors:  Nevan J Krogan; Gerard Cagney; Haiyuan Yu; Gouqing Zhong; Xinghua Guo; Alexandr Ignatchenko; Joyce Li; Shuye Pu; Nira Datta; Aaron P Tikuisis; Thanuja Punna; José M Peregrín-Alvarez; Michael Shales; Xin Zhang; Michael Davey; Mark D Robinson; Alberto Paccanaro; James E Bray; Anthony Sheung; Bryan Beattie; Dawn P Richards; Veronica Canadien; Atanas Lalev; Frank Mena; Peter Wong; Andrei Starostine; Myra M Canete; James Vlasblom; Samuel Wu; Chris Orsi; Sean R Collins; Shamanta Chandran; Robin Haw; Jennifer J Rilstone; Kiran Gandi; Natalie J Thompson; Gabe Musso; Peter St Onge; Shaun Ghanny; Mandy H Y Lam; Gareth Butland; Amin M Altaf-Ul; Shigehiko Kanaya; Ali Shilatifard; Erin O'Shea; Jonathan S Weissman; C James Ingles; Timothy R Hughes; John Parkinson; Mark Gerstein; Shoshana J Wodak; Andrew Emili; Jack F Greenblatt
Journal:  Nature       Date:  2006-03-22       Impact factor: 49.962

9.  How complete are current yeast and human protein-interaction networks?

Authors:  G Traver Hart; Arun K Ramani; Edward M Marcotte
Journal:  Genome Biol       Date:  2006       Impact factor: 13.583

10.  Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae.

Authors:  Teresa Reguly; Ashton Breitkreutz; Lorrie Boucher; Bobby-Joe Breitkreutz; Nizar N Batada; Gary C Hon; Chad L Myers; Ainslie Parsons; Helena Friesen; Rose Oughtred; Amy Tong; Chris Stark; Yuen Ho; David Botstein; Brenda Andrews; Charles Boone; Olga G Troyanskya; Trey Ideker; Kara Dolinski; Mike Tyers
Journal:  J Biol       Date:  2006-06-08
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  6 in total

Review 1.  Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review.

Authors:  Peter Csermely; Tamás Korcsmáros; Huba J M Kiss; Gábor London; Ruth Nussinov
Journal:  Pharmacol Ther       Date:  2013-02-04       Impact factor: 12.310

2.  Inferring functional communities from partially observed biological networks exploiting geometric topology and side information.

Authors:  Jayson Sia; Wei Zhang; Edmond Jonckheere; David Cook; Paul Bogdan
Journal:  Sci Rep       Date:  2022-06-27       Impact factor: 4.996

3.  Generating social network data using partially described networks: an example informing avian influenza control in the British poultry industry.

Authors:  Sema Nickbakhsh; Louise Matthews; Paul R Bessell; Stuart W J Reid; Rowland R Kao
Journal:  BMC Vet Res       Date:  2011-10-25       Impact factor: 2.741

4.  Assembling real networks from synthetic and unstructured subsets: the corporate reporting case.

Authors:  Eduardo Viegas; Hayato Goto; Misako Takayasu; Hideki Takayasu; Henrik Jeldtoft Jensen
Journal:  Sci Rep       Date:  2019-07-30       Impact factor: 4.379

5.  Gaining confidence in inferred networks.

Authors:  Léo P M Diaz; Michael P H Stumpf
Journal:  Sci Rep       Date:  2022-02-14       Impact factor: 4.379

6.  Multi-model and network inference based on ensemble estimates: avoiding the madness of crowds.

Authors:  Michael P H Stumpf
Journal:  J R Soc Interface       Date:  2020-10-21       Impact factor: 4.118

  6 in total

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