Literature DB >> 20378023

An uncommon case of systemic Mucormycosis associated with spinal cord infarction in a recently diagnosed diabetic.

A Giuliani1, M Mettimano, D Viviani, A Scagliusi, A Bruno, A Russo, M Rotoli, L Savi.   

Abstract

Mucormycosis is a relatively rare, opportunistic, invasive infection caused by various members of the Phycomycetes class [from Greek phyko- seaweed; having a plant body], an extensive taxonomy introduced in 1956 to enlarge the class of Zygomycetes. These filamentous fungi have a worldwide distribution and are capable of rapid growth and thermotolerance of human body temperature. Infection typically occurs in seriously compromised patients (i.e. diabetic ketoacidosis, hematologic malignancies, immunosuppressive disorders, end-stage renal disease, solid-organ or bone-marrow transplantation) and can be acute or fulminant, as well as indolent and chronic. In this paper we describe a case of cutaneous mucormycosis that occurred in a 54-year-old diabetic woman and evolved into a disseminated form, leading to an uncommon spinal cord infarction and consequent paraparesis. Our case suggests the importance of suspecting a mucormycosis infection in patients with decompensated diabetes mellitus, even without ketoacidosis.

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Year:  2010        PMID: 20378023     DOI: 10.1177/039463201002300135

Source DB:  PubMed          Journal:  Int J Immunopathol Pharmacol        ISSN: 0394-6320            Impact factor:   3.219


  3 in total

1.  Mucormycosis of the Spine: A Case Report and Review of the Literature.

Authors:  Jaimin Patel; Zach Pennington; Andrew M Hersh; Bethany Hung; Daniel M Scuibba; Sheng-Fu L Lo
Journal:  Cureus       Date:  2022-03-29

2.  Infections in patients with diabetes mellitus: A review of pathogenesis.

Authors:  Juliana Casqueiro; Janine Casqueiro; Cresio Alves
Journal:  Indian J Endocrinol Metab       Date:  2012-03

Review 3.  Paraplegia secondary to disseminated mucormycosis: case report and literature review.

Authors:  Xiangjun Shi; Lei Qi; Boran Du; Xingchen Yao; Xinru Du
Journal:  BMC Infect Dis       Date:  2022-04-25       Impact factor: 3.667

  3 in total

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