CONCLUSION: With half-sized cupula, the semicircular canal nerve potentials decreased under slow stimulus, thus potentially leading to reduced caloric response. This also suggests that shrunken cupula may cause dizziness because of its hypermobility. OBJECTIVES: To examine the physiological effect of half-sized cupula on the semicircular canal nerve potential. METHODS: The isolated cupula of the bullfrog was sectioned in half with fine scissors and was replaced on the crista. Mechanical endolymphatic flow and slow and fast stimuli were delivered and the evoked action potentials were recorded. RESULTS: The cupula was successfully sectioned in half and was replaced on the crista. With the half-sized cupula, the action potentials became smaller under slow stimulus than under fast stimulus.
CONCLUSION: With half-sized cupula, the semicircular canal nerve potentials decreased under slow stimulus, thus potentially leading to reduced caloric response. This also suggests that shrunken cupula may cause dizziness because of its hypermobility. OBJECTIVES: To examine the physiological effect of half-sized cupula on the semicircular canal nerve potential. METHODS: The isolated cupula of the bullfrog was sectioned in half with fine scissors and was replaced on the crista. Mechanical endolymphatic flow and slow and fast stimuli were delivered and the evoked action potentials were recorded. RESULTS: The cupula was successfully sectioned in half and was replaced on the crista. With the half-sized cupula, the action potentials became smaller under slow stimulus than under fast stimulus.
Authors: Jens Dernedde; Christoph Weise; Eva-Christina Müller; Akira Hagiwara; Sebastian Bachmann; Mamoru Suzuki; Werner Reutter; Rudolf Tauber; Hans Scherer Journal: PLoS One Date: 2014-11-04 Impact factor: 3.240