PURPOSE: To investigate the potential of multi-slice computed tomography (MSCT) as a tool for non-invasive temperature measurement. MATERIALS AND METHODS: Samples of water, 0.9% saline, sunflower oil and dilutions of (1:32, 1:64, 1:128) contrast agent (Iopromid 370, BayerSchering Pharma, Berlin) were heated in a plexiglass phantom. In a first set-up, samples of 0.9% saline solution were scanned at defined temperatures (25 degrees -75 degrees C; 5 degrees C intervals) using a clinical CT scanner. Scan parameters (tube current-time product, tube voltage, collimation, slice thickness) were systematically varied. In a second set-up samples of the different fluids (water, sunflower oil, contrast agent dilutions) were scanned using the following scan protocol: 250 mAs, 140 kV, 1.2 mm collimation, 9.6 mm slice thickness. CT numbers were measured in reconstructed axial images at the different temperatures. A regression analysis was performed to investigate the relationship between temperature and CT number. RESULTS: Standard deviation of measured CT numbers decreased with increasing tube current-time product, increasing tube voltage, thicker collimation and higher slice thickness. Regression analysis showed an inverse relationship between temperature and CT number for all fluids with regression coefficients of -0.471 (0.9% saline), 0.447 (water), -0.679 (sunflower oil), -0.420 (contrast agent 1:32), -0.414 (contrast agent 1:64) and -0.441 (contrast agent 1:128), respectively. CONCLUSION: Multi-slice computed tomography can depict thermal density expansion of different fluids. Based on these results the implementation of a temperature discrimination of several degrees C at a high spatial resolution is achievable.
PURPOSE: To investigate the potential of multi-slice computed tomography (MSCT) as a tool for non-invasive temperature measurement. MATERIALS AND METHODS: Samples of water, 0.9% saline, sunflower oil and dilutions of (1:32, 1:64, 1:128) contrast agent (Iopromid 370, BayerSchering Pharma, Berlin) were heated in a plexiglass phantom. In a first set-up, samples of 0.9% saline solution were scanned at defined temperatures (25 degrees -75 degrees C; 5 degrees C intervals) using a clinical CT scanner. Scan parameters (tube current-time product, tube voltage, collimation, slice thickness) were systematically varied. In a second set-up samples of the different fluids (water, sunflower oil, contrast agent dilutions) were scanned using the following scan protocol: 250 mAs, 140 kV, 1.2 mm collimation, 9.6 mm slice thickness. CT numbers were measured in reconstructed axial images at the different temperatures. A regression analysis was performed to investigate the relationship between temperature and CT number. RESULTS: Standard deviation of measured CT numbers decreased with increasing tube current-time product, increasing tube voltage, thicker collimation and higher slice thickness. Regression analysis showed an inverse relationship between temperature and CT number for all fluids with regression coefficients of -0.471 (0.9% saline), 0.447 (water), -0.679 (sunflower oil), -0.420 (contrast agent 1:32), -0.414 (contrast agent 1:64) and -0.441 (contrast agent 1:128), respectively. CONCLUSION: Multi-slice computed tomography can depict thermal density expansion of different fluids. Based on these results the implementation of a temperature discrimination of several degrees C at a high spatial resolution is achievable.
Authors: G D Pandeya; J H G M Klaessens; M J W Greuter; B Schmidt; T Flohr; R van Hillegersberg; M Oudkerk Journal: Eur Radiol Date: 2011-03-24 Impact factor: 5.315
Authors: Andreas Heinrich; Sebastian Schenkl; David Buckreus; Felix V Güttler; Ulf K-M Teichgräber Journal: Eur Radiol Date: 2021-07-29 Impact factor: 5.315