Literature DB >> 20376063

Is the filaggrin-histidine-urocanic acid pathway essential for stratum corneum acidification?

Joachim W Fluhr, Peter M Elias, Mao-Qiang Man, Melanie Hupe, Clare Selden, John P Sundberg, Erwin Tschachler, Leopold Eckhart, Theodora M Mauro, Kenneth R Feingold.   

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Year:  2010        PMID： 20376063      PMCID： PMC4548931          DOI： 10.1038/jid.2010.74

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


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  24 in total

1.  Generation of free fatty acids from phospholipids regulates stratum corneum acidification and integrity.

Authors:  J W Fluhr; J Kao; M Jain; S K Ahn; K R Feingold; P M Elias
Journal:  J Invest Dermatol       Date:  2001-07       Impact factor: 8.551

2.  Sustained serine proteases activity by prolonged increase in pH leads to degradation of lipid processing enzymes and profound alterations of barrier function and stratum corneum integrity.

Authors:  Jean-Pierre Hachem; Mao-Quiang Man; Debra Crumrine; Yoshikazu Uchida; Barbara E Brown; Vera Rogiers; Diane Roseeuw; Kenneth R Feingold; Peter M Elias
Journal:  J Invest Dermatol       Date:  2005-09       Impact factor: 8.551

3.  The importance of lipids in cutaneous function.

Authors:  Kennenth R Feingold
Journal:  J Lipid Res       Date:  2007-12       Impact factor: 5.922

4.  Differences in the skin surface pH and bacterial microflora due to the long-term application of synthetic detergent preparations of pH 5.5 and pH 7.0. Results of a crossover trial in healthy volunteers.

Authors:  H C Korting; K Hübner; K Greiner; G Hamm; O Braun-Falco
Journal:  Acta Derm Venereol       Date:  1990       Impact factor: 4.437

5.  Evidence for the existence of a self-regulated enzymatic process within the human stratum corneum -an unexpected role for urocanic acid.

Authors:  P M Krien; M Kermici
Journal:  J Invest Dermatol       Date:  2000-09       Impact factor: 8.551

6.  Effect of the lactic acid bacterium Streptococcus thermophilus on ceramide levels in human keratinocytes in vitro and stratum corneum in vivo.

Authors:  L Di Marzio; B Cinque; C De Simone; M G Cifone
Journal:  J Invest Dermatol       Date:  1999-07       Impact factor: 8.551

7.  Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing.

Authors:  T Mauro; W M Holleran; S Grayson; W N Gao; M Q Man; E Kriehuber; M Behne; K R Feingold; P M Elias
Journal:  Arch Dermatol Res       Date:  1998-04       Impact factor: 3.017

8.  The roles of pH and concentration in lactic acid-induced stimulation of epidermal turnover.

Authors:  D O Thueson; E K Chan; L M Oechsli; G S Hahn
Journal:  Dermatol Surg       Date:  1998-06       Impact factor: 3.398

9.  Histidinemia in mice: a metabolic defect treated using a novel approach to hepatocellular transplantation.

Authors:  C Selden; D Calnan; N Morgan; H Wilcox; E Carr; H J Hodgson
Journal:  Hepatology       Date:  1995-05       Impact factor: 17.425

Review 10.  The skin barrier as an innate immune element.

Authors:  Peter M Elias
Journal:  Semin Immunopathol       Date:  2007-04       Impact factor: 11.759
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  20 in total

1.  Atopic March from Atopic Dermatitis to Asthma-Like Lesions in NC/Nga Mice Is Accelerated or Aggravated by Neutralization of Stratum Corneum but Partially Inhibited by Acidification.

Authors:  Hae-Jin Lee; Noo Ri Lee; Minyoung Jung; Dong Hye Kim; Eung Ho Choi
Journal:  J Invest Dermatol       Date:  2015-08-26       Impact factor: 8.551

Review 2.  Pathogenesis of Dermatophytosis: Sensing the Host Tissue.

Authors:  Nilce M Martinez-Rossi; Nalu T A Peres; Antonio Rossi
Journal:  Mycopathologia       Date:  2016-09-02       Impact factor: 2.574

Review 3.  Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis.

Authors:  Sang Eun Lee; Se Kyoo Jeong; Seung Hun Lee
Journal:  Yonsei Med J       Date:  2010-11       Impact factor: 2.759

4.  Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct.

Authors:  Kateřina Vávrová; Dominika Henkes; Kay Strüver; Michaela Sochorová; Barbora Školová; Madeleine Y Witting; Wolfgang Friess; Stephan Schreml; Robert J Meier; Monika Schäfer-Korting; Joachim W Fluhr; Sarah Küchler
Journal:  J Invest Dermatol       Date:  2013-09-23       Impact factor: 8.551

5.  sPLA2 and the epidermal barrier.

Authors:  Dusko Ilic; James M Bollinger; Michael Gelb; Theodora M Mauro
Journal:  Biochim Biophys Acta       Date:  2013-11-20

6.  Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation.

Authors:  Valérie Pendaries; Jeremy Malaisse; Laurence Pellerin; Marina Le Lamer; Rachida Nachat; Sanja Kezic; Anne-Marie Schmitt; Carle Paul; Yves Poumay; Guy Serre; Michel Simon
Journal:  J Invest Dermatol       Date:  2014-06-13       Impact factor: 8.551

7.  Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.

Authors:  Robert Gruber; Peter M Elias; Debra Crumrine; Tzu-Kai Lin; Johanna M Brandner; Jean-Pierre Hachem; Richard B Presland; Philip Fleckman; Andreas R Janecke; Aileen Sandilands; W H Irwin McLean; Peter O Fritsch; Michael Mildner; Erwin Tschachler; Matthias Schmuth
Journal:  Am J Pathol       Date:  2011-05       Impact factor: 4.307

8.  Acidification in the epidermis and the role of secretory phospholipases.

Authors:  Aegean Chan; Theodora Mauro
Journal:  Dermatoendocrinol       Date:  2011-04-01

Review 9.  Skin barrier disruption: a requirement for allergen sensitization?

Authors:  Anna De Benedetto; Akiharu Kubo; Lisa A Beck
Journal:  J Invest Dermatol       Date:  2012-01-05       Impact factor: 8.551

Review 10.  One remarkable molecule: filaggrin.

Authors:  Sara J Brown; W H Irwin McLean
Journal:  J Invest Dermatol       Date:  2011-12-08       Impact factor: 8.551
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