Literature DB >> 20376052

Endoplasmic reticulum stress and atherosclerosis.

Gökhan S Hotamisligil1.   

Abstract

Atherosclerosis and related cardiovascular diseases represent one of the greatest threats to human health worldwide. Despite important progress in prevention and treatment, these conditions still account for one third of all deaths annually. Often presented together with obesity, insulin resistance and type 2 diabetes, these chronic diseases are strongly influenced by pathways that lie at the interface of chronic inflammation and nutrient metabolism. Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its complications.

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Year:  2010        PMID： 20376052      PMCID： PMC2897068          DOI： 10.1038/nm0410-396

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


  50 in total

1.  Monocytic origin of foam cells in human atherosclerotic plaques.

Authors:  N M Aqel; R Y Ball; H Waldmann; M J Mitchinson
Journal:  Atherosclerosis       Date:  1984-12       Impact factor: 5.162

2.  Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis.

Authors:  Liza Makowski; Jeffrey B Boord; Kazuhisa Maeda; Vladimir R Babaev; K Teoman Uysal; Maureen A Morgan; Rex A Parker; Jill Suttles; Sergio Fazio; Gökhan S Hotamisligil; MacRae F Linton
Journal:  Nat Med       Date:  2001-06       Impact factor: 53.440

3.  Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes.

Authors:  Umut Ozcan; Qiong Cao; Erkan Yilmaz; Ann-Hwee Lee; Neal N Iwakoshi; Esra Ozdelen; Gürol Tuncman; Cem Görgün; Laurie H Glimcher; Gökhan S Hotamisligil
Journal:  Science       Date:  2004-10-15       Impact factor: 47.728

4.  GM1-ganglioside-mediated activation of the unfolded protein response causes neuronal death in a neurodegenerative gangliosidosis.

Authors:  Alessandra Tessitore; Maria del P Martin; Renata Sano; Yanjun Ma; Linda Mann; Angela Ingrassia; Eric D Laywell; Dennis A Steindler; Linda M Hendershot; Alessandra d'Azzo
Journal:  Mol Cell       Date:  2004-09-10       Impact factor: 17.970

5.  Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

Authors:  Haiyan Xu; Glenn T Barnes; Qing Yang; Guo Tan; Daseng Yang; Chieh J Chou; Jason Sole; Andrew Nichols; Jeffrey S Ross; Louis A Tartaglia; Hong Chen
Journal:  J Clin Invest       Date:  2003-12       Impact factor: 14.808

6.  A central role for JNK in obesity and insulin resistance.

Authors:  Jiro Hirosumi; Gürol Tuncman; Lufen Chang; Cem Z Görgün; K Teoman Uysal; Kazuhisa Maeda; Michael Karin; Gökhan S Hotamisligil
Journal:  Nature       Date:  2002-11-21       Impact factor: 49.962

7.  Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta.

Authors:  Sasanka Ramanadham; Fong-Fu Hsu; Sheng Zhang; Chun Jin; Alan Bohrer; Haowei Song; Shunzhong Bao; Zhongmin Ma; John Turk
Journal:  Biochemistry       Date:  2004-02-03       Impact factor: 3.162

8.  The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages.

Authors:  Bo Feng; Pin Mei Yao; Yankun Li; Cecilia M Devlin; Dajun Zhang; Heather P Harding; Michele Sweeney; James X Rong; George Kuriakose; Edward A Fisher; Andrew R Marks; David Ron; Ira Tabas
Journal:  Nat Cell Biol       Date:  2003-08-10       Impact factor: 28.824

9.  Normalization of obesity-associated insulin resistance through immunotherapy.

Authors:  Shawn Winer; Yin Chan; Geoffrey Paltser; Dorothy Truong; Hubert Tsui; Jasmine Bahrami; Ruslan Dorfman; Yongqian Wang; Julian Zielenski; Fabrizio Mastronardi; Yuko Maezawa; Daniel J Drucker; Edgar Engleman; Daniel Winer; H-Michael Dosch
Journal:  Nat Med       Date:  2009-07-26       Impact factor: 53.440

10.  XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

Authors:  Rungtawan Sriburi; Suzanne Jackowski; Kazutoshi Mori; Joseph W Brewer
Journal:  J Cell Biol       Date:  2004-10-04       Impact factor: 10.539
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  118 in total

Review 1.  Endoplasmic reticulum stress, redox, and a proinflammatory environment in athero-susceptible endothelium in vivo at sites of complex hemodynamic shear stress.

Authors:  Peter F Davies; Mete Civelek
Journal:  Antioxid Redox Signal       Date:  2011-05-25       Impact factor: 8.401

Review 2.  Nutrition and metabolic correlates of obesity and inflammation: clinical considerations.

Authors:  Amy R Johnson; Liza Makowski
Journal:  J Nutr       Date:  2015-04-01       Impact factor: 4.798

Review 3.  Atherosclerosis: current pathogenesis and therapeutic options.

Authors:  Christian Weber; Heidi Noels
Journal:  Nat Med       Date:  2011-11-07       Impact factor: 53.440

4.  RLIP76 protein knockdown attenuates obesity due to a high-fat diet.

Authors:  Sharad S Singhal; James Figarola; Jyotsana Singhal; Marpadga A Reddy; Xueli Liu; David Berz; Rama Natarajan; Sanjay Awasthi
Journal:  J Biol Chem       Date:  2013-07-02       Impact factor: 5.157

Review 5.  Inflammatory mechanisms linking obesity and metabolic disease.

Authors:  Alan R Saltiel; Jerrold M Olefsky
Journal:  J Clin Invest       Date:  2017-01-03       Impact factor: 14.808

Review 6.  Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders.

Authors:  Yu Cai; Jyothi Arikkath; Lu Yang; Ming-Lei Guo; Palsamy Periyasamy; Shilpa Buch
Journal:  Autophagy       Date:  2016       Impact factor: 16.016

7.  The spread of adenoviral vectors to central nervous system through pathway of cochlea in mimetic aging and young rats.

Authors:  X Chen; X Zhao; Y Hu; F Lan; H Sun; G Fan; Y Sun; J Wu; W Kong; W Kong
Journal:  Gene Ther       Date:  2015-06-30       Impact factor: 5.250

8.  Establishment of a system for monitoring endoplasmic reticulum redox state in mammalian cells.

Authors:  Kohsuke Kanekura; Shinsuke Ishigaki; Philip I Merksamer; Feroz R Papa; Fumihiko Urano
Journal:  Lab Invest       Date:  2013-09-16       Impact factor: 5.662

Review 9.  Role of endoplasmic reticulum stress signalling in diabetic endothelial dysfunction and atherosclerosis.

Authors:  Yunzhou Dong; Conrad Fernandes; Yanjun Liu; Yong Wu; Hao Wu; Megan L Brophy; Lin Deng; Kai Song; Aiyun Wen; Scott Wong; Daoguang Yan; Rheal Towner; Hong Chen
Journal:  Diab Vasc Dis Res       Date:  2016-10-20       Impact factor: 3.291

10.  Possible role of fibroblast growth factor 21 on atherosclerosis via amelioration of endoplasmic reticulum stress-mediated apoptosis in apoE(-/-) mice.

Authors:  Xi Wu; Yong-Fen Qi; Jin-Rui Chang; Wei-Wei Lu; Jin-Sheng Zhang; Shao-Ping Wang; Shu-Juan Cheng; Ming Zhang; Qian Fan; Yuan Lv; Hui Zhu; Man-Kun Xin; Yun Lv; Jing-Hua Liu
Journal:  Heart Vessels       Date:  2014-08-05       Impact factor: 2.037
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