Literature DB >> 20375626

Protective role of complement C5a in an experimental model of Staphylococcus aureus bacteremia.

Maren von Köckritz-Blickwede1, Stephanie Konrad, Simon Foster, J Engelbert Gessner, Eva Medina.   

Abstract

The complement system is a key component of the innate immune response. Here, we have examined the role of complement anaphylatoxin C5a in an experimental model of Staphylococcus aureus bacteremia. Our data provide compelling evidence for a protective role of C5a during staphylococcal bloodstream infection. (c) 2009 S. Karger AG, Basel.

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Year:  2009        PMID： 20375626     DOI： 10.1159/000247157

Source DB:  PubMed          Journal:  J Innate Immun        ISSN： 1662-811X            Impact factor:   7.349


  13 in total

1.  The effect of human complement C3 protein applied at different times in treatment of polymicrobial sepsis.

Authors:  Yujie Yuan; Jianan Ren; Guosheng Gu; Shougen Cao; Jieshou Li
Journal:  Inflamm Res       Date:  2012-02-16       Impact factor: 4.575

2.  Functional basis for complement evasion by staphylococcal superantigen-like 7.

Authors:  Jovanka Bestebroer; Piet C Aerts; Suzan H M Rooijakkers; Manoj K Pandey; Jörg Köhl; Jos A G van Strijp; Carla J C de Haas
Journal:  Cell Microbiol       Date:  2010-10       Impact factor: 3.715

Review 3.  Procession to pediatric bacteremia and sepsis: covert operations and failures in diplomacy.

Authors:  Stacey L Bateman; Patrick C Seed
Journal:  Pediatrics       Date:  2010-06-21       Impact factor: 7.124

4.  Staphylococcus aureus virulence is enhanced by secreted factors that block innate immune defenses.

Authors:  Ilse Jongerius; Maren von Köckritz-Blickwede; Malcolm J Horsburgh; Maartje Ruyken; Victor Nizet; Suzan H M Rooijakkers
Journal:  J Innate Immun       Date:  2012-02-07       Impact factor: 7.349

5.  Elevated serum interleukin-10 at time of hospital admission is predictive of mortality in patients with Staphylococcus aureus bacteremia.

Authors:  Warren E Rose; Jens C Eickhoff; Sanjay K Shukla; Madhulatha Pantrangi; Suzan Rooijakkers; Sara E Cosgrove; Victor Nizet; George Sakoulas
Journal:  J Infect Dis       Date:  2012-09-10       Impact factor: 5.226

Review 6.  Complement in immune and inflammatory disorders: therapeutic interventions.

Authors:  Daniel Ricklin; John D Lambris
Journal:  J Immunol       Date:  2013-04-15       Impact factor: 5.422

7.  Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.

Authors:  Sun-Hee Ahn; Hitesh Deshmukh; Nicole Johnson; Lindsay G Cowell; Thomas H Rude; William K Scott; Charlotte L Nelson; Aimee K Zaas; Douglas A Marchuk; Sehoon Keum; Supaporn Lamlertthon; Batu K Sharma-Kuinkel; Gregory D Sempowski; Vance G Fowler
Journal:  PLoS Pathog       Date:  2010-09-02       Impact factor: 6.823

8.  Differential Contributions of the Complement Anaphylotoxin Receptors C5aR1 and C5aR2 to the Early Innate Immune Response against Staphylococcus aureus Infection.

Authors:  Sarah A Horst; Andreas Itzek; Andreas Klos; Andreas Beineke; Eva Medina
Journal:  Pathogens       Date:  2015-10-23

9.  Deficiency of the Complement Component 3 but Not Factor B Aggravates Staphylococcus aureus Septic Arthritis in Mice.

Authors:  Manli Na; Anders Jarneborn; Abukar Ali; Amanda Welin; Malin Magnusson; Anna Stokowska; Marcela Pekna; Tao Jin
Journal:  Infect Immun       Date:  2016-03-24       Impact factor: 3.441

10.  Complement levels in patients with bloodstream infection due to Staphylococcus aureus or Gram-negative bacteria.

Authors:  Emily M Eichenberger; Michael Dagher; Felicia Ruffin; Lawrence Park; Lisa Hersh; Sumathi Sivapalasingam; Vance G Fowler; Brinda C Prasad
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2020-07-04       Impact factor: 5.103
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