| Literature DB >> 20375614 |
Kelly L Brown1, Karin Christenson, Anna Karlsson, Claes Dahlgren, Johan Bylund.
Abstract
Clearance of senescent cells from damaged tissue is a crucial step to successfully resolve an inflammatory response. Poor clearance has been attributed to defects in neutrophil apoptosis, a process that is regulated in part by reactive oxygen species (ROS) produced by activated neutrophils. Using ROS-deficient and wild-type macrophages treated with extracellular ROS scavengers we demonstrate that macrophage-derived ROS also influence phagocytosis and do so by direct and indirect mechanisms. (c) 2009 S. Karger AG, Basel.Entities:
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Year: 2009 PMID： 20375614 DOI： 10.1159/000235583
Source DB: PubMed Journal: J Innate Immun ISSN： 1662-811X Impact factor: 7.349