Literature DB >> 20375446

An ontology for description of drug discovery investigations.

Da Qi1, Ross D King, Andrew L Hopkins, G Richard J Bickerton, Larisa N Soldatova.   

Abstract

The paper presents an ontology for the description of Drug Discovery Investigation (DDI).This has been developed through the use of a Robot Scientist "Eve", and in consultation with industry. DDI aims to define the principle entities and the relations in the research and development phase of the drug discovery pipeline. DDI is highly transferable and extendable due to its adherence to accepted standards, and compliance with existing ontology resources. This enables DDI to be integrated with such related ontologies as the Vaccine Ontology, the Advancing Clinico-Genomic Trials on Cancer Master Ontology, etc. DDI is available at http://purl.org/ddi/wikipedia or http://purl.org/ddi/home.

Mesh：

Year:  2010        PMID： 20375446     DOI： 10.2390/biecoll-jib-2010-126

Source DB:  PubMed          Journal:  J Integr Bioinform        ISSN： 1613-4516


  16 in total

1.  Summarizing and visualizing structural changes during the evolution of biomedical ontologies using a Diff Abstraction Network.

Authors:  Christopher Ochs; Yehoshua Perl; James Geller; Melissa Haendel; Matthew Brush; Sivaram Arabandi; Samson Tu
Journal:  J Biomed Inform       Date:  2015-06-03       Impact factor: 6.317

2.  A tribal abstraction network for SNOMED CT target hierarchies without attribute relationships.

Authors:  Christopher Ochs; James Geller; Yehoshua Perl; Yan Chen; Ankur Agrawal; James T Case; George Hripcsak
Journal:  J Am Med Inform Assoc       Date:  2014-10-20       Impact factor: 4.497

3.  Utilizing a structural meta-ontology for family-based quality assurance of the BioPortal ontologies.

Authors:  Christopher Ochs; Zhe He; Ling Zheng; James Geller; Yehoshua Perl; George Hripcsak; Mark A Musen
Journal:  J Biomed Inform       Date:  2016-03-14       Impact factor: 6.317

Review 4.  Abstraction networks for terminologies: Supporting management of "big knowledge".

Authors:  Michael Halper; Huanying Gu; Yehoshua Perl; Christopher Ochs
Journal:  Artif Intell Med       Date:  2015-04-02       Impact factor: 5.326

5.  An empirical analysis of ontology reuse in BioPortal.

Authors:  Christopher Ochs; Yehoshua Perl; James Geller; Sivaram Arabandi; Tania Tudorache; Mark A Musen
Journal:  J Biomed Inform       Date:  2017-06-02       Impact factor: 6.317

Review 6.  Minimum information about a bioactive entity (MIABE).

Authors:  Sandra Orchard; Bissan Al-Lazikani; Steve Bryant; Dominic Clark; Elizabeth Calder; Ian Dix; Ola Engkvist; Mark Forster; Anna Gaulton; Michael Gilson; Robert Glen; Martin Grigorov; Kim Hammond-Kosack; Lee Harland; Andrew Hopkins; Christopher Larminie; Nick Lynch; Romeena K Mann; Peter Murray-Rust; Elena Lo Piparo; Christopher Southan; Christoph Steinbeck; David Wishart; Henning Hermjakob; John Overington; Janet Thornton
Journal:  Nat Rev Drug Discov       Date:  2011-08-31       Impact factor: 84.694

7.  Quality assurance of chemical ingredient classification for the National Drug File - Reference Terminology.

Authors:  Ling Zheng; Hasan Yumak; Ling Chen; Christopher Ochs; James Geller; Joan Kapusnik-Uner; Yehoshua Perl
Journal:  J Biomed Inform       Date:  2017-07-16       Impact factor: 6.317

Review 8.  Introducing the Big Knowledge to Use (BK2U) challenge.

Authors:  Yehoshua Perl; James Geller; Michael Halper; Christopher Ochs; Ling Zheng; Joan Kapusnik-Uner
Journal:  Ann N Y Acad Sci       Date:  2016-10-17       Impact factor: 5.691

Review 9.  Empowering industrial research with shared biomedical vocabularies.

Authors:  Lee Harland; Christopher Larminie; Susanna-Assunta Sansone; Sorana Popa; M Scott Marshall; Michael Braxenthaler; Michael Cantor; Wendy Filsell; Mark J Forster; Enoch Huang; Andreas Matern; Mark Musen; Jasmin Saric; Ted Slater; Jabe Wilson; Nick Lynch; John Wise; Ian Dix
Journal:  Drug Discov Today       Date:  2011-09-23       Impact factor: 7.851

10.  Visual comprehension and orientation into the COVID-19 CIDO ontology.

Authors:  Ling Zheng; Yehoshua Perl; Yongqun He; Christopher Ochs; James Geller; Hao Liu; Vipina K Keloth
Journal:  J Biomed Inform       Date:  2021-07-02       Impact factor: 8.000
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