Literature DB >> 20375362

Training translators for smart drug discovery.

Carsten Skarke1, Garret A FitzGerald.   

Abstract

To achieve advances in clinical medicine, we need investigators with a sophisticated understanding of medicine and pharmacology who are capable of projecting their preclinical research across the translational divide. Such expertise in translational medicine and therapeutics has become scant in academia, industry, and regulatory bodies. Here we discuss strategies for addressing this deficit in human capital.

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Year:  2010        PMID: 20375362     DOI: 10.1126/scitranslmed.3000890

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN: 1946-6234            Impact factor:   17.956


  8 in total

1.  Evolution in translational science: Whither the CTSAs?

Authors:  Garret A FitzGerald
Journal:  Sci Transl Med       Date:  2015-04-22       Impact factor: 17.956

2.  Clinical translational science 2020: disruptive innovation redefines the discovery-application enterprise.

Authors:  Scott A Waldman; Andre Terzic
Journal:  Clin Transl Sci       Date:  2011-02       Impact factor: 4.689

3.  Systems vaccinomics: the road ahead for vaccinology.

Authors:  Alan Bernstein; Bali Pulendran; Rino Rappuoli
Journal:  OMICS       Date:  2011-08-09

4.  Clinical pharmacology at the core of translational science.

Authors:  Scott A Waldman; Andre Terzic
Journal:  Expert Rev Clin Pharmacol       Date:  2011-05       Impact factor: 5.045

Review 5.  Testing cardiovascular drug safety and efficacy in randomized trials.

Authors:  Garret A FitzGerald
Journal:  Circ Res       Date:  2014-03-28       Impact factor: 17.367

6.  Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS).

Authors:  Harry Shamoon; David Center; Pamela Davis; Mendel Tuchman; Henry Ginsberg; Robert Califf; David Stephens; Thomas Mellman; Joseph Verbalis; Lee Nadler; Anantha Shekhar; Daniel Ford; Robert Rizza; Reza Shaker; Kathleen Brady; Barbara Murphy; Bruce Cronstein; Judith Hochman; Philip Greenland; Eric Orwoll; Lawrence Sinoway; Harry Greenberg; Rebecca Jackson; Barry Coller; Eric Topol; Lisa Guay-Woodford; Marschall Runge; Robert Clark; Don McClain; Harry Selker; Curtis Lowery; Steven Dubinett; Lars Berglund; Dan Cooper; Gary Firestein; S Clay Johnston; Julian Solway; James Heubi; Ronald Sokol; David Nelson; Larry Tobacman; Gary Rosenthal; Lauren Aaronson; Richard Barohn; Philip Kern; John Sullivan; Thomas Shanley; Bruce Blazar; Richard Larson; Garret FitzGerald; Steven Reis; Thomas Pearson; Thomas Buchanan; David McPherson; Allan Brasier; Robert Toto; Mary Disis; Marc Drezner; Gordon Bernard; John Clore; Bradley Evanoff; Julianne Imperato-McGinley; Robert Sherwin; Jill Pulley
Journal:  Clin Transl Sci       Date:  2012-03-27       Impact factor: 4.689

Review 7.  Training translators in the PENN CTSA.

Authors:  Emma A Meagher
Journal:  Clin Transl Sci       Date:  2011-10       Impact factor: 4.689

8.  Academia Europaea Position Paper on Translational Medicine: The Cycle Model for Translating Scientific Results into Community Benefits.

Authors:  Péter Hegyi; Ole H Petersen; Stephen Holgate; Bálint Erőss; András Garami; Zsolt Szakács; Dalma Dobszai; Márta Balaskó; Lajos Kemény; Shuang Peng; Joao Monteiro; András Varró; Tara Lamont; Jeffrey Laurence; Zoe Gray; Andrew Pickles; Garret A FitzGerald; Christopher E M Griffiths; Jacek Jassem; Dmitri A Rusakov; Alexei Verkhratsky; Andrea Szentesi
Journal:  J Clin Med       Date:  2020-05-19       Impact factor: 4.241

  8 in total

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