Chanchal Gera1, Amarjit Singh Vij. 1. Department of Medicine, Christian Medical College & Hospital, Ludhiana, Punjab. cgera@rediffmail.com
Abstract
BACKGROUND: The burden of osteoporosis is on the rise and glucocorticoids are one of the leading causes of drug-induced osteoporosis. According to available guidelines, patients on long-term glucocorticoid therapy should receive adequate prophylaxis to prevent osteoporosis. OBJECTIVES: To compare prescription patterns in relation to Royal College of Physicians (RCP) Guidelines 2002. To identify prescribing trends for prophylaxis and management of steroid-induced osteoporosis. METHODS: We conducted a retrospective audit for patients in a tertiary care center to determine whether clinicians are evaluating and appropriately following prophylactic guidelines for corticoid-induced osteoporosis. Information regarding risk assessment for osteoporosis, instructions regarding its prevention, bone mineral density measurements, and prophylactic therapy were recorded. RESULTS: One hundred and five patients (38 men and 67 women), more then 18 years of age were included in this study. Of the 105 patients, 56% had at least one documented intervention for osteoporosis prevention (calcium, vitamin D, bisphosphonates or a bone mineral density study). Only three patients received bisphosphonates for osteoporosis prophylaxis. CONCLUSION: The study shows poor pre-therapeutic risk assessment, absence of instructions regarding preventive measures, inappropriate investigation for presence of osteoporosis, and unacceptable absence of bone protective agents.
BACKGROUND: The burden of osteoporosis is on the rise and glucocorticoids are one of the leading causes of drug-induced osteoporosis. According to available guidelines, patients on long-term glucocorticoid therapy should receive adequate prophylaxis to prevent osteoporosis. OBJECTIVES: To compare prescription patterns in relation to Royal College of Physicians (RCP) Guidelines 2002. To identify prescribing trends for prophylaxis and management of steroid-induced osteoporosis. METHODS: We conducted a retrospective audit for patients in a tertiary care center to determine whether clinicians are evaluating and appropriately following prophylactic guidelines for corticoid-induced osteoporosis. Information regarding risk assessment for osteoporosis, instructions regarding its prevention, bone mineral density measurements, and prophylactic therapy were recorded. RESULTS: One hundred and five patients (38 men and 67 women), more then 18 years of age were included in this study. Of the 105 patients, 56% had at least one documented intervention for osteoporosis prevention (calcium, vitamin D, bisphosphonates or a bone mineral density study). Only three patients received bisphosphonates for osteoporosis prophylaxis. CONCLUSION: The study shows poor pre-therapeutic risk assessment, absence of instructions regarding preventive measures, inappropriate investigation for presence of osteoporosis, and unacceptable absence of bone protective agents.
Authors: Flávia Carmo Horta Pinto; Armando Da Silva-Cunha Junior; Rodrigo Lambert Oréfice; Eliane Ayres; Silvia Passos Andrade; Luiza Dias C Lima; Sandra A Lima Moura; Gisele Rodrigues Da Silva Journal: J Mater Sci Mater Med Date: 2012-04-01 Impact factor: 3.896
Authors: Sophie Trijau; Gaëlle de Lamotte; Vincent Pradel; François Natali; Véronique Allaria-Lapierre; Hervé Coudert; Thao Pham; Vincent Sciortino; Pierre Lafforgue Journal: RMD Open Date: 2016-07-07