| Literature DB >> 20373736 |
Leah Shin1, Won Jin Cho, Jeremy D Cook, Timothy L Stemmler, Bhanu P Jena.
Abstract
Approximately 11% smaller t-/v-SNARE ring complexes are generated using 50 nm cholesterol-associated vesicles as opposed to vesicles containing L-alpha-lysophosphatidylcholine (LPC), as observed using atomic force microscopy. Circular dichroism spectroscopy demonstrated that in the presence of LPC as opposed to cholesterol, N-ethylmaleimide-sensitive factor + adenosine triphosphate induces disassembly of beta-sheet structures but not the alpha-helical contents within the t-/v-SNARE complex.Entities:
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Year: 2010 PMID： 20373736 PMCID： PMC2862647 DOI： 10.1021/ja101574d
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419