Literature DB >> 20372088

The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E.

Selvaraju Veeriah, Luc Morris, David Solit, Timothy A Chan.   

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Year:  2010        PMID: 20372088      PMCID: PMC2921461          DOI: 10.4161/cc.9.8.11583

Source DB:  PubMed          Journal:  Cell Cycle        ISSN: 1551-4005            Impact factor:   4.534


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  11 in total

1.  Association between early-onset Parkinson's disease and mutations in the parkin gene.

Authors:  C B Lücking; A Dürr; V Bonifati; J Vaughan; G De Michele; T Gasser; B S Harhangi; G Meco; P Denèfle; N W Wood; Y Agid; A Brice
Journal:  N Engl J Med       Date:  2000-05-25       Impact factor: 91.245

2.  Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer.

Authors:  A Letessier; S Garrido-Urbani; C Ginestier; G Fournier; B Esterni; F Monville; J Adélaïde; J Geneix; L Xerri; P Dubreuil; P Viens; E Charafe-Jauffret; J Jacquemier; D Birnbaum; M Lopez; M Chaffanet
Journal:  Oncogene       Date:  2006-07-03       Impact factor: 9.867

3.  Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity.

Authors:  John F Staropoli; Caroline McDermott; Cécile Martinat; Brenda Schulman; Elena Demireva; Asa Abeliovich
Journal:  Neuron       Date:  2003-03-06       Impact factor: 17.173

4.  Deregulated cyclin E induces chromosome instability.

Authors:  C H Spruck; K A Won; S I Reed
Journal:  Nature       Date:  1999-09-16       Impact factor: 49.962

Review 5.  Parkin-associated Parkinson's disease.

Authors:  Rainer von Coelln; Valina L Dawson; Ted M Dawson
Journal:  Cell Tissue Res       Date:  2004-07-30       Impact factor: 5.249

6.  Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27.

Authors:  Rossano Cesari; Eric S Martin; George A Calin; Francesca Pentimalli; Roberta Bichi; Holly McAdams; Francesco Trapasso; Alessandra Drusco; Masayoshi Shimizu; Valeria Masciullo; Giuseppina D'Andrilli; Giovanni Scambia; Maria Cristina Picchio; Hansjuerg Alder; Andrew K Godwin; Carlo M Croce
Journal:  Proc Natl Acad Sci U S A       Date:  2003-04-28       Impact factor: 11.205

7.  Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.

Authors:  Selvaraju Veeriah; Barry S Taylor; Shasha Meng; Fang Fang; Emrullah Yilmaz; Igor Vivanco; Manickam Janakiraman; Nikolaus Schultz; Aphrothiti J Hanrahan; William Pao; Marc Ladanyi; Chris Sander; Adriana Heguy; Eric C Holland; Philip B Paty; Paul S Mischel; Linda Liau; Timothy F Cloughesy; Ingo K Mellinghoff; David B Solit; Timothy A Chan
Journal:  Nat Genet       Date:  2009-11-29       Impact factor: 38.330

8.  Cyclin E deregulation is an early event in the development of breast cancer.

Authors:  Alexandra Shaye; Aysegul Sahin; Qiang Hao; Kelly Hunt; Khandan Keyomarsi; Isabelle Bedrosian
Journal:  Breast Cancer Res Treat       Date:  2008-12-24       Impact factor: 4.872

9.  An integrated genomic analysis of human glioblastoma multiforme.

Authors:  D Williams Parsons; Siân Jones; Xiaosong Zhang; Jimmy Cheng-Ho Lin; Rebecca J Leary; Philipp Angenendt; Parminder Mankoo; Hannah Carter; I-Mei Siu; Gary L Gallia; Alessandro Olivi; Roger McLendon; B Ahmed Rasheed; Stephen Keir; Tatiana Nikolskaya; Yuri Nikolsky; Dana A Busam; Hanna Tekleab; Luis A Diaz; James Hartigan; Doug R Smith; Robert L Strausberg; Suely Kazue Nagahashi Marie; Sueli Mieko Oba Shinjo; Hai Yan; Gregory J Riggins; Darell D Bigner; Rachel Karchin; Nick Papadopoulos; Giovanni Parmigiani; Bert Vogelstein; Victor E Velculescu; Kenneth W Kinzler
Journal:  Science       Date:  2008-09-04       Impact factor: 47.728

10.  Comprehensive genomic characterization defines human glioblastoma genes and core pathways.

Authors: 
Journal:  Nature       Date:  2008-09-04       Impact factor: 49.962

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  18 in total

Review 1.  Role of cell cycle re-entry in neurons: a common apoptotic mechanism of neuronal cell death.

Authors:  Jaume Folch; Felix Junyent; Ester Verdaguer; Carme Auladell; Javier G Pizarro; Carlos Beas-Zarate; Mercè Pallàs; Antoni Camins
Journal:  Neurotox Res       Date:  2011-10-01       Impact factor: 3.911

Review 2.  RBR E3-ligases at work.

Authors:  Judith J Smit; Titia K Sixma
Journal:  EMBO Rep       Date:  2014-01-27       Impact factor: 8.807

3.  Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins.

Authors:  Yongxing Gong; Travis Ian Zack; Luc G T Morris; Kan Lin; Ellen Hukkelhoven; Radhika Raheja; I-Li Tan; Sevin Turcan; Selvaraju Veeriah; Shasha Meng; Agnes Viale; Steven E Schumacher; Perry Palmedo; Rameen Beroukhim; Timothy A Chan
Journal:  Nat Genet       Date:  2014-05-04       Impact factor: 38.330

4.  Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy.

Authors:  Néstor Prieto-Domínguez; Raquel Ordóñez; Anna Fernández; Carolina Méndez-Blanco; Anna Baulies; Carmen Garcia-Ruiz; José C Fernández-Checa; José L Mauriz; Javier González-Gallego
Journal:  J Pineal Res       Date:  2016-08-19       Impact factor: 13.007

5.  Parkin New Cargos: a New ROS Independent Role for Parkin in Regulating Cell Division.

Authors:  David C Stieg; Katrina F Cooper
Journal:  React Oxyg Species (Apex)       Date:  2016

Review 6.  Autophagy and Hallmarks of Cancer.

Authors:  Tianzhi Huang; Xiao Song; Yongyong Yang; Xuechao Wan; Angel A Alvarez; Namratha Sastry; Haizhong Feng; Bo Hu; Shi-Yuan Cheng
Journal:  Crit Rev Oncog       Date:  2018

Review 7.  Leprosy and the human genome.

Authors:  Elizabeth A Misch; William R Berrington; James C Vary; Thomas R Hawn
Journal:  Microbiol Mol Biol Rev       Date:  2010-12       Impact factor: 11.056

Review 8.  Pathologic and therapeutic implications for the cell biology of parkin.

Authors:  Rakshita A Charan; Matthew J LaVoie
Journal:  Mol Cell Neurosci       Date:  2015-02-17       Impact factor: 4.314

Review 9.  Parkin in Parkinson's Disease and Cancer: a Double-Edged Sword.

Authors:  Khushnuma Wahabi; Ahmad Perwez; Moshahid A Rizvi
Journal:  Mol Neurobiol       Date:  2018-01-18       Impact factor: 5.590

10.  Unraveling 50-Year-Old Clues Linking Neurodegeneration and Cancer to Cycad Toxins: Are microRNAs Common Mediators?

Authors:  Peter Spencer; Rebecca C Fry; Glen E Kisby
Journal:  Front Genet       Date:  2012-09-28       Impact factor: 4.599

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