Literature DB >> 20371469

Optimizing the delivery of cancer drugs that block angiogenesis.

Yihai Cao1, Robert Langer.   

Abstract

Drugs that block angiogenesis are important components of first-line therapies for a number of human cancers. However, some of these agents have undesirable effects on the patient. Optimal delivery systems must be developed to maximize clinical benefits and minimize adverse effects in cancer patients. In this Perspective, we discuss these drug-related issues and propose ways to optimize antiangiogenic therapy by the development of new drug delivery systems.

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Year:  2010        PMID： 20371469     DOI： 10.1126/scitranslmed.3000399

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  33 in total

Review 1.  Adipocyte and lipid metabolism in cancer drug resistance.

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2.  Localization of magnetic pills.

Authors:  Bryan Laulicht; Nicholas J Gidmark; Anubhav Tripathi; Edith Mathiowitz
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-21       Impact factor: 11.205

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Journal:  Proc Natl Acad Sci U S A       Date:  2015-05-19       Impact factor: 11.205

Review 4.  Gentian violet: a 19th century drug re-emerges in the 21st century.

Authors:  Alexander M Maley; Jack L Arbiser
Journal:  Exp Dermatol       Date:  2013-12       Impact factor: 3.960

Review 5.  Off-tumor target--beneficial site for antiangiogenic cancer therapy?

Authors:  Yihai Cao
Journal:  Nat Rev Clin Oncol       Date:  2010-08-03       Impact factor: 66.675

6.  Antiangiogenic agents significantly improve survival in tumor-bearing mice by increasing tolerance to chemotherapy-induced toxicity.

Authors:  Danfang Zhang; Eva-Maria E Hedlund; Sharon Lim; Fang Chen; Yin Zhang; Baocun Sun; Yihai Cao
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-18       Impact factor: 11.205

7.  Clock controls angiogenesis.

Authors:  Lasse Dahl Jensen; Yihai Cao
Journal:  Cell Cycle       Date:  2013-01-16       Impact factor: 4.534

Review 8.  Customizable biomaterials as tools for advanced anti-angiogenic drug discovery.

Authors:  Eric H Nguyen; William L Murphy
Journal:  Biomaterials       Date:  2018-07-26       Impact factor: 12.479

9.  Sequential release of nanoparticle payloads from ultrasonically burstable capsules.

Authors:  Stephen Kennedy; Jennifer Hu; Cathal Kearney; Hadas Skaat; Luo Gu; Marco Gentili; Herman Vandenburgh; David Mooney
Journal:  Biomaterials       Date:  2015-10-22       Impact factor: 12.479

10.  Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy.

Authors:  Nathaniel Huebsch; Cathal J Kearney; Xuanhe Zhao; Jaeyun Kim; Christine A Cezar; Zhigang Suo; David J Mooney
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-24       Impact factor: 11.205
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