PURPOSE: To describe an atypical case of primary intraocular lymphoma (PIOL) with rapid progression leading to vision loss and death. METHODS: A 71-year-old woman with a history of PIOL presented with a sudden decline in vision. MRI, CSF cytology, and ocular examination 2 months prior were unremarkable. RESULTS: Repeat MRI of the brain and orbits at this time revealed a 0.8 x 2.4-cm lesion of the left choroid plexus. LP revealed rare atypical B cells. The patient rapidly deteriorated and died a month later. CONCLUSION: Recognition of the potential for rapid progression and mortality in patients with PIOL is essential.
PURPOSE: To describe an atypical case of primary intraocular lymphoma (PIOL) with rapid progression leading to vision loss and death. METHODS: A 71-year-old woman with a history of PIOL presented with a sudden decline in vision. MRI, CSF cytology, and ocular examination 2 months prior were unremarkable. RESULTS: Repeat MRI of the brain and orbits at this time revealed a 0.8 x 2.4-cm lesion of the left choroid plexus. LP revealed rare atypical B cells. The patient rapidly deteriorated and died a month later. CONCLUSION: Recognition of the potential for rapid progression and mortality in patients with PIOL is essential.
Authors: S A Grimm; J S Pulido; K Jahnke; D Schiff; A J Hall; T N Shenkier; T Siegal; N D Doolittle; T Batchelor; U Herrlinger; E A Neuwelt; N Laperriere; M C Chamberlain; J Y Blay; A J M Ferreri; A M P Omuro; E Thiel; L E Abrey Journal: Ann Oncol Date: 2007-09-05 Impact factor: 32.976