Literature DB >> 20367713

Quantitative evaluation of a clinical intervention aimed at changing prescriber behaviour in response to new guidelines.

Sophie Doyon1, Mélissa Perreault, Christopher Marquis, Josianne Gauthier, Denis Lebel, Benoit Bailey, Johanne Collin, Jean-François Bussières.   

Abstract

RATIONAL, AIMS AND
OBJECTIVES: The objective of the study was to assess prescribers' compliance with guidelines for acute community-acquired pneumonia management in a paediatric university hospital centre before and after its dissemination.
METHOD: This quasi-experimental study without a control group was conducted before and after new community-acquired pneumonia management guidelines were disseminated in a tertiary care paediatric hospital. The pre-intervention (baseline) period was from October 2004 to March 2005. The intervention period was divided into two phases: (1) October 2005 to January 14, 2006 (consultation by peer leaders and networking) and (2) January 15, 2006, to March 2006 (dissemination of official guidelines and of a pre-printed prescription sheet, an educational session led by a peer leader for residents and further networking). We used a compliance score to assess prescriptions written by prescribers who practised in the units where the guidelines had to be followed.
RESULTS: The study included a total of 1151 prescriptions. The prescription compliance with the guidelines increased from 131/652 (20.1%) in the pre-intervention period to 264/499 (52.9%) in the post-intervention intervention period: a difference of 32.8% (CI 95% 27.4-38.0). Similar results were found if analysed according to affiliation (emergency department or wards). An inappropriate choice of antibiotic agent represented 347/521 (66.6%) of the causes of non-compliance in the pre-intervention period and 99/235 (42.1) in the intervention period: a difference of -24.5% (95% CI -31.8, -16.8).
CONCLUSION: Guideline dissemination for the management of acute community-acquired pneumonia significantly increased prescriber compliance in the emergency department and on wards.

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Year:  2009        PMID: 20367713     DOI: 10.1111/j.1365-2753.2009.01259.x

Source DB:  PubMed          Journal:  J Eval Clin Pract        ISSN: 1356-1294            Impact factor:   2.431


  4 in total

Review 1.  In-Hospital Macro-, Meso-, and Micro-Drivers and Interventions for Antibiotic Use and Resistance: A Rapid Evidence Synthesis of Data from Canada and Other OECD Countries.

Authors:  Rosa Stalteri Mastrangelo; Anisa Hajizadeh; Thomas Piggott; Mark Loeb; Michael Wilson; Luis Enrique Colunga Lozano; Yetiani Roldan; Hussein El-Khechen; Anna Miroshnychenko; Priya Thomas; Holger J Schünemann; Robby Nieuwlaat
Journal:  Can J Infect Dis Med Microbiol       Date:  2022-03-16       Impact factor: 2.585

2.  A novel clinical pharmacy management system in improving the rational drug use in department of general surgery.

Authors:  L Bao; Y Wang; T Shang; X Ren; R Ma
Journal:  Indian J Pharm Sci       Date:  2013-01       Impact factor: 0.975

Review 3.  Implementation and impact of pediatric antimicrobial stewardship programs: a systematic scoping review.

Authors:  D Donà; E Barbieri; M Daverio; R Lundin; C Giaquinto; T Zaoutis; M Sharland
Journal:  Antimicrob Resist Infect Control       Date:  2020-01-03       Impact factor: 4.887

Review 4.  Social and professional influences on antimicrobial prescribing for doctors-in-training: a realist review.

Authors:  Chrysanthi Papoutsi; Karen Mattick; Mark Pearson; Nicola Brennan; Simon Briscoe; Geoff Wong
Journal:  J Antimicrob Chemother       Date:  2017-09-01       Impact factor: 5.790

  4 in total

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