Literature DB >> 20367584

Depression and obesity in adults with asthma: multiple comorbidities and management issues.

David H Wilson1, Sarah L Appleton, Anne W Taylor, Graeme Tucker, Richard E Ruffin, Gary Wittert, Graeme Hugo, Robert D Goldney, Christopher Findlay, Robert J Adams.   

Abstract

OBJECTIVE: To examine the comparative prevalence and distribution of obesity and psychological disturbance in the asthma and non-asthma populations, and to determine how these comorbidities are associated with physical functioning. DESIGN, SETTING AND PARTICIPANTS: A South Australian population-representative study of 3175 adults who provided data on asthma, psychological morbidity, physical functioning, and body mass index. Bivariate and multivariate analyses identified how these comorbidities were distributed in asthma and non-asthma subpopulations, and the variance in physical functioning that they explained. MAIN OUTCOME MEASURES: Rates of obesity and psychological morbidity, and physical functioning scores in asthma and non-asthma populations.
RESULTS: Men and women in the asthma population had similar prevalences of obesity (35.3% v 33.6%) and psychological morbidity (29.5% v 29.4%). When compared with non-asthma controls, both comorbidities were significantly higher only in men with asthma. The prevalence of psychological morbidity within different weight categories in the asthma population compared with non-asthma weight-category controls varied by sex. Physical functioning was lower in the asthma population than the non-asthma population (46.6 [95% CI, 45.9-47.3] v 48.8 [95% CI, 47.8-50.0]; P < 0.001), and psychological morbidity explained 22% of this variance.
CONCLUSIONS: Psychological morbidity and obesity are common in people with asthma. The sex-specific variation in psychological morbidity across weight categories suggests that future studies of psychological morbidity in groups with asthma should adopt designs that consider sex-specific controls rather than comparisons between the sexes.

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Year:  2010        PMID: 20367584     DOI: 10.5694/j.1326-5377.2010.tb03559.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  5 in total

1.  Results from several population studies show that recommended scoring methods of the SF-36 and the SF-12 may lead to incorrect conclusions and subsequent health decisions.

Authors:  Graeme Tucker; Robert Adams; David Wilson
Journal:  Qual Life Res       Date:  2014-03-20       Impact factor: 4.147

2.  Early life environment and developmental immunotoxicity in inflammatory dysfunction and disease.

Authors:  Cynthia A Leifer; Rodney R Dietert
Journal:  Toxicol Environ Chem       Date:  2011       Impact factor: 1.437

3.  Obesity and symptoms of depression contribute independently to the poor asthma control of obesity.

Authors:  S G Kapadia; C Wei; S J Bartlett; J Lang; R A Wise; A E Dixon
Journal:  Respir Med       Date:  2014-06-09       Impact factor: 3.415

4.  Depressiveness, symptoms of anxiety and cognitive dysfunctions in patients with asthma and chronic obstructive pulmonary disease (COPD): possible associations with inflammation markers: a pilot study.

Authors:  Agnieszka Bratek; Karolina Zawada; Julia Beil-Gawełczyk; Sonia Beil; Ewa Sozańska; Krzysztof Krysta; Adam Barczyk; Irena Krupka-Matuszczyk; Władysław Pierzchała
Journal:  J Neural Transm (Vienna)       Date:  2014-02-15       Impact factor: 3.575

5.  Asparagus cochinchinensis extract ameliorates menopausal depression in ovariectomized rats under chronic unpredictable mild stress.

Authors:  Hye Ryeong Kim; Young-Ju Lee; Tae-Wan Kim; Ri-Na Lim; Dae Youn Hwang; Jeffrey J Moffat; Soonil Kim; Joung-Wook Seo; Minhan Ka
Journal:  BMC Complement Med Ther       Date:  2020-10-27
  5 in total

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