Literature DB >> 20364872

Use of the Diels-Alder adduct of pyrrole in organic synthesis. Formal racemic synthesis of Tamiflu.

Akio Kamimura1, Toshiki Nakano.   

Abstract

A new synthetic route to Tamiflu was developed via the Diels-Alder reaction of pyrrole and bromoacetylene.

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Year:  2010        PMID： 20364872     DOI： 10.1021/jo1002856

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  3 in total

1.  Development of a concise synthesis of (-)-oseltamivir (Tamiflu).

Authors:  Barry M Trost; Ting Zhang
Journal:  Chemistry       Date:  2011-03-01       Impact factor: 5.236

2.  Diethyl 1,8-bis-(4-methyl-phen-yl)-11-oxatricyclo-[6.2.1.0(2,7)]undeca-2,4,6-triene-9,10-dicarboxyl-ate.

Authors:  B Balakrishnan; Meganathan Nandakumar; Pandamangalam R Seshadri; Arasambattu K Mohanakrishnan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-03-06

3.  Synthesis of highly functionalized β-aminocyclopentanecarboxylate stereoisomers by reductive ring opening reaction of isoxazolines.

Authors:  Melinda Nonn; Loránd Kiss; Reijo Sillanpää; Ferenc Fülöp
Journal:  Beilstein J Org Chem       Date:  2012-01-17       Impact factor: 2.883
  3 in total

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