Literature DB >> 20364437

Highly effective treatment with tacrolimus ointment in an adolescent with oral graft-versus-host disease.

T Bauters1, V Bordon, V Van de Velde, S Van Lancker, H Robays, Y Benoit, G Laureys.   

Abstract

CASE: We report a case of acute oral graft-versus-host disease in an adolescent, which was successfully treated with tacrolimus 0.1% ointment.
CONCLUSION: Although tacrolimus ointment is not licensed for the indication of oral GvHD, this case report provides preliminary evidence for a potential effectiveness of using tacrolimus in case of failure when GvHD is resistant.

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Year:  2010        PMID: 20364437     DOI: 10.1007/s11096-010-9386-9

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  7 in total

Review 1.  Chronic graft versus host disease of oral mucosa: review of available therapies.

Authors:  Matin M Imanguli; Steven Z Pavletic; Jean-Pierre Guadagnini; Jaime S Brahim; Jane C Atkinson
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2006-02

2.  Long-term efficacy of topical tacrolimus on oral lesions of chronic graft-versus-host disease.

Authors:  J-C Fricain; V Sibaud; N Swetyenga; R Tabrizi; F Campana; A Taïeb
Journal:  Br J Dermatol       Date:  2007-03       Impact factor: 9.302

3.  Toxic serum levels of tacrolimus after topical administration in an infant with severe cutaneous graft-versus-host disease.

Authors:  S Prot-Labarthe; R Therrien; M A Champagne; M Duval; C Joubert
Journal:  Bone Marrow Transplant       Date:  2007-06-04       Impact factor: 5.483

Review 4.  Oral graft-versus-host disease.

Authors:  M M Imanguli; I Alevizos; R Brown; S Z Pavletic; J C Atkinson
Journal:  Oral Dis       Date:  2008-07       Impact factor: 3.511

5.  Oral graft vs. host disease in children--treatment with topical tacrolimus ointment.

Authors:  Michael H Albert; B Becker; F R Schuster; B Klein; V Binder; K Adam; C Nienhoff; M Führer; A Borkhardt
Journal:  Pediatr Transplant       Date:  2007-05

6.  Severe oral chronic graft-versus-host disease following allogeneic bone marrow transplantation: highly effective treatment with topical tacrolimus.

Authors:  André Eckardt; Oliver Starke; Michael Stadler; Christoph Reuter; Bernd Hertenstein
Journal:  Oral Oncol       Date:  2004-09       Impact factor: 5.337

Review 7.  Acute graft-versus-host disease: new treatment strategies.

Authors:  Sophie Paczesny; Sung W Choi; James L M Ferrara
Journal:  Curr Opin Hematol       Date:  2009-11       Impact factor: 3.284

  7 in total

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