Literature DB >> 20363802

Role of extracellular DNA in initial bacterial adhesion and surface aggregation.

Theerthankar Das1, Prashant K Sharma, Henk J Busscher, Henny C van der Mei, Bastiaan P Krom.   

Abstract

Extracellular DNA (eDNA) is an important component of the biofilm matrix. We show that removal of eDNA from Gram-positive bacteria reduces initial adhesion to and aggregation of bacteria on surfaces. Thermodynamic analyses indicated that eDNA introduces favorable acid-base interactions, explaining the effect of eDNA on aggregation and adhesion to the surface.

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Year:  2010        PMID: 20363802      PMCID: PMC2869138          DOI: 10.1128/AEM.03119-09

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  13 in total

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6.  DNA as an adhesin: Bacillus cereus requires extracellular DNA to form biofilms.

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  82 in total

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Review 4.  Control of Biofilm Formation: Antibiotics and Beyond.

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6.  Competence-Stimulating-Peptide-Dependent Localized Cell Death and Extracellular DNA Production in Streptococcus mutans Biofilms.

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Review 9.  The exopolysaccharide matrix: a virulence determinant of cariogenic biofilm.

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