Literature DB >> 20362823

Chondrolysis of the glenohumeral joint after infusion of bupivacaine through an intra-articular pain pump catheter: a report of 18 cases.

S Lance Anderson1, Jordan Z Buchko, Mario R Taillon, Mark A Ernst.   

Abstract

PURPOSE: To report on our experience of patients who received infusion of bupivacaine with epinephrine after arthroscopic glenoid labral repair surgery and in whom glenohumeral joint chondrolysis subsequently developed, as well as to determine the incidence of such chondrolysis in our surgeons' patient populations.
METHODS: A retrospective chart review of 18 patients diagnosed with chondrolysis was carried out. All patients were from 2 experienced orthopaedic surgeons' practices. Details of their clinical course were obtained and summarized. These data were compared with all other arthroscopies completed by the 2 surgeons to determine the incidence of chondrolysis.
RESULTS: All 18 patients diagnosed with glenohumeral joint chondrolysis received postoperative infusion of bupivacaine with epinephrine through an intra-articular pain pump catheter (IAPPC). None of the patients received thermal energy as part of their procedure. None of the patients had evidence of glenohumeral joint infection, although an extensive workup was frequently undertaken. Clinically, patients presented with a stiff, painful shoulder. Examination showed decreased range of motion of the affected shoulder. Radiographs and magnetic resonance imaging showed joint space narrowing, as well as subchondral sclerosis and cyst formation. Of the 18 patients, 14 have since undergone repeat arthroscopic procedures, and 5 have received a humeral head-resurfacing operation. Within the same time period, there were 113 arthroscopies, with 45 pain pumps used. Chondrolysis developed in 16 of 32 patients with high-flow IAPPCs and 2 of 12 patients with low-flow IAPPCs (1 patient's IAPPC flow rate was not documented).
CONCLUSIONS: Although we cannot establish a causal link, the development of glenohumeral chondrolysis may be related to the intra-articular infusion of bupivacaine with epinephrine postoperatively. We thus caution against the use of IAPPCs. LEVEL OF EVIDENCE: Level IV, therapeutic case series. Copyright 2010 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20362823     DOI: 10.1016/j.arthro.2010.01.022

Source DB:  PubMed          Journal:  Arthroscopy        ISSN: 0749-8063            Impact factor:   4.772


  19 in total

1.  The effect of local anaesthetics on synoviocytes: a possible indirect mechanism of chondrolysis.

Authors:  Hillary J Braun; Benjamin T Busfield; Hyeon Joo Kim; Gaetano J Scuderi; Jason L Dragoo
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-06-21       Impact factor: 4.342

2.  Complications after arthroscopic labral repair for shoulder instability.

Authors:  Keisuke Matsuki; Hiroyuki Sugaya
Journal:  Curr Rev Musculoskelet Med       Date:  2015-03

3.  Rotator cuff healing after continuous subacromial bupivacaine infusion: an in vivo rabbit study.

Authors:  Nicole A Friel; Vincent M Wang; Mark A Slabaugh; FanChia Wang; Susan Chubinskaya; Brian J Cole
Journal:  J Shoulder Elbow Surg       Date:  2012-07-20       Impact factor: 3.019

4.  Opioids as an alternative to amide-type local anaesthetics for intra-articular application.

Authors:  Irina Ickert; Monika Herten; Melanie Vogl; Christoph Ziskoven; Christoph Zilkens; Rüdiger Krauspe; Jörn Kircher
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-05-04       Impact factor: 4.342

5.  The effect of local anesthetic and corticosteroid combinations on chondrocyte viability.

Authors:  Hillary J Braun; Nathaniel Wilcox-Fogel; Hyeon Joo Kim; Michael A Pouliot; Alex H S Harris; Jason L Dragoo
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-10-29       Impact factor: 4.342

Review 6.  Effect of various factors on articular cartilage and their implications on arthroscopic procedures: A review of literature.

Authors:  Sandeep Kohli; Varun Tandra; Abhinav Gulihar
Journal:  J Clin Orthop Trauma       Date:  2019-06-20

Review 7.  Single-dose local anesthetics exhibit a type-, dose-, and time-dependent chondrotoxic effect on chondrocytes and cartilage: a systematic review of the current literature.

Authors:  Peter Cornelius Kreuz; Matthias Steinwachs; Peter Angele
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-03-13       Impact factor: 4.342

8.  Randomized, controlled trial of multimodal shoulder injection or intravenous patient-controlled analgesia after arthroscopic rotator cuff repair.

Authors:  Sun Sook Han; Ye Hyun Lee; Joo Han Oh; Susan Aminzai; Sae Hoon Kim
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-09-19       Impact factor: 4.342

9.  Comparison of intra-articular low-dose sufentanil, ropivacaine, and combined sufentanil and ropivacaine on post-operative analgesia of isolated anterior cruciate ligament reconstruction.

Authors:  Xin Wang; Donglin Jia; Xiuyun Chen; Yan Xu
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-12-08       Impact factor: 4.342

10.  Articular cartilage and local anaesthetic: A systematic review of the current literature.

Authors:  Abhinav Gulihar; Shibby Robati; Haider Twaij; Alan Salih; Grahame J S Taylor
Journal:  J Orthop       Date:  2015-10-31
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