Literature DB >> 20361366

[Clinical research in partnership: musculoskeletal surgery].

G N Duda1, S Benusch, N P Haas.   

Abstract

As a result of the demographic development of industrial nations the number of musculoskeletal diseases and injuries rises continuously. This challenges health care as well as clinical research and demands additional endeavours. The United Nations have recognised this issue at an early stage. With their in 2000 declared Bone and Joint Decade they have significantly contributed to a sustainable support of research activities. The German government has also perceived the need and, with their roadmap programme, encourages research of musculoskeletal disease.Today, surgical and orthopaedic clinics increasingly support the exchange between research and clinic and run their own research departments. The Berlin Center for Musculoskeletal Surgery (CMSC) and its research institute Julius Wolff Institut show the potential for surgical research. It shows that based on a clinical understanding of the problem, basic research needs to be complemented in a network with partners from other disciplines. However, interdisciplinary cooperation demands new and individual ways of communication and education. The example in Berlin also illustrates that the research on prevention not only completes the network but more over opens unexpected possibilities in understanding basic research and translation.

Entities:  

Mesh:

Year:  2010        PMID: 20361366     DOI: 10.1007/s00104-009-1836-3

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  6 in total

1.  Timely fracture-healing requires optimization of axial fixation stability.

Authors:  Devakara R Epari; Jean-Pierre Kassi; Hanna Schell; Georg N Duda
Journal:  J Bone Joint Surg Am       Date:  2007-07       Impact factor: 5.284

2.  Spatial and temporal variations of mechanical properties and mineral content of the external callus during bone healing.

Authors:  I Manjubala; Y Liu; D R Epari; P Roschger; H Schell; P Fratzl; G N Duda
Journal:  Bone       Date:  2009-05-03       Impact factor: 4.398

3.  Validation of beta-actin used as endogenous control for gene expression analysis in mechanobiology studies: amendments.

Authors:  Grit Kasper; Andrea Ode; Aline Groothuis; Juliane Glaeser; Timo Gaber; Cameron J Wilson; Sven Geissler; Georg N Duda
Journal:  Stem Cells       Date:  2010-03-31       Impact factor: 6.277

Review 4.  Biomechanical, microvascular, and cellular factors promote muscle and bone regeneration.

Authors:  Georg N Duda; William R Taylor; Tobias Winkler; Georg Matziolis; Markus O Heller; Norbert P Haas; Carsten Perka; Klaus-D Schaser
Journal:  Exerc Sport Sci Rev       Date:  2008-04       Impact factor: 6.230

5.  Instability prolongs the chondral phase during bone healing in sheep.

Authors:  Devakara R Epari; Hanna Schell; Hermann J Bail; Georg N Duda
Journal:  Bone       Date:  2005-12-15       Impact factor: 4.398

6.  Matrix metalloprotease activity is an essential link between mechanical stimulus and mesenchymal stem cell behavior.

Authors:  Grit Kasper; Juliane D Glaeser; Sven Geissler; Andrea Ode; Jens Tuischer; Georg Matziolis; Carsten Perka; Georg N Duda
Journal:  Stem Cells       Date:  2007-05-10       Impact factor: 6.277

  6 in total

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