Literature DB >> 20361095

Total synthesis of (+)-stachyflin: a potential anti-influenza A virus agent.

Kazuhiro Watanabe1, Junji Sakurai, Hideki Abe, Tadashi Katoh.   

Abstract

The first enantioselective total synthesis of (+)-stachyflin, a potential anti-influenza A virus agent, was achieved; the method features a BF(3).Et(2)O-induced domino epoxide-opening/rearrangement/cyclization reaction to stereoselectively form the requisite pentacyclic ring system in one step.

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Year:  2010        PMID： 20361095     DOI： 10.1039/c000193g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

Review 1.  An invocation for computational evaluation of isomerization transforms: cationic skeletal reorganizations as a case study.

Authors:  Alexander W Schuppe; Yannan Liu; Timothy R Newhouse
Journal:  Nat Prod Rep       Date:  2020-09-15       Impact factor: 13.423

2.  Enantioselective Total Synthesis and Structural Revision of Dysiherbol A.

Authors:  Julian Baars; Isabelle Grimm; Dirk Blunk; Jörg-Martin Neudörfl; Hans-Günther Schmalz
Journal:  Angew Chem Int Ed Engl       Date:  2021-06-01       Impact factor: 15.336

Review 3.  Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus.

Authors:  R Gasparini; D Amicizia; P L Lai; N L Bragazzi; D Panatto
Journal:  J Prev Med Hyg       Date:  2014-12

4.  A modular synthesis of tetracyclic meroterpenoid antibiotics.

Authors:  Raphael Wildermuth; Klaus Speck; Franz-Lucas Haut; Peter Mayer; Bianka Karge; Mark Brönstrup; Thomas Magauer
Journal:  Nat Commun       Date:  2017-12-12       Impact factor: 14.919

5.  Unexpected Racemization in the Course of the Acetalization of (+)-(S)-5-Methyl-Wieland-Miescher Ketone with 1,2-Ethanediol and TsOH under Classical Experimental Conditions.

Authors:  Francesca Leonelli; Irene Piergentili; Giulio Lucarelli; Luisa Maria Migneco; Rinaldo Marini Bettolo
Journal:  Int J Mol Sci       Date:  2019-12-05       Impact factor: 5.923

6.  First total synthesis of ampullosine, a unique isoquinoline alkaloid isolated from Sepedonium ampullosporum, and of the related permethylampullosine.

Authors:  Didier F Vargas; Enrique L Larghi; Teodoro S Kaufman
Journal:  RSC Adv       Date:  2019-10-16       Impact factor: 4.036

7.  A Concise Route for the Synthesis of Tetracyclic Meroterpenoids: (±)-Aureol Preparation and Mechanistic Interpretation.

Authors:  Antonio Rosales Martínez; Lourdes Enríquez; Martín Jaraíz; Laura Pozo Morales; Ignacio Rodríguez-García; Emilio Díaz Ojeda
Journal:  Mar Drugs       Date:  2020-08-26       Impact factor: 5.118
  7 in total

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