Literature DB >> 20360728

Drug discovery: Fat-free proteins kill parasites.

George A M Cross.   

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Year:  2010        PMID： 20360728     DOI： 10.1038/464689a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  7 in total

1.  Hydrodynamic flow-mediated protein sorting on the cell surface of trypanosomes.

Authors:  Markus Engstler; Thomas Pfohl; Stephan Herminghaus; Michael Boshart; Geert Wiegertjes; Niko Heddergott; Peter Overath
Journal:  Cell       Date:  2007-11-02       Impact factor: 41.582

Review 2.  Target assessment for antiparasitic drug discovery.

Authors:  Julie A Frearson; Paul G Wyatt; Ian H Gilbert; Alan H Fairlamb
Journal:  Trends Parasitol       Date:  2007-10-24

3.  Myristoyl-CoA:protein N-myristoyltransferase, an essential enzyme and potential drug target in kinetoplastid parasites.

Authors:  Helen P Price; Malini R Menon; Chrysoula Panethymitaki; David Goulding; Paul G McKean; Deborah F Smith
Journal:  J Biol Chem       Date:  2002-12-17       Impact factor: 5.157

Review 4.  Trafficking and signaling by fatty-acylated and prenylated proteins.

Authors:  Marilyn D Resh
Journal:  Nat Chem Biol       Date:  2006-11       Impact factor: 15.040

5.  Myristyl amino-terminal acylation of murine retrovirus proteins: an unusual post-translational proteins modification.

Authors:  L E Henderson; H C Krutzsch; S Oroszlan
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205

6.  N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.

Authors:  Julie A Frearson; Stephen Brand; Stuart P McElroy; Laura A T Cleghorn; Ondrej Smid; Laste Stojanovski; Helen P Price; M Lucia S Guther; Leah S Torrie; David A Robinson; Irene Hallyburton; Chidochangu P Mpamhanga; James A Brannigan; Anthony J Wilkinson; Michael Hodgkinson; Raymond Hui; Wei Qiu; Olawale G Raimi; Daan M F van Aalten; Ruth Brenk; Ian H Gilbert; Kevin D Read; Alan H Fairlamb; Michael A J Ferguson; Deborah F Smith; Paul G Wyatt
Journal:  Nature       Date:  2010-04-01       Impact factor: 49.962

7.  Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects.

Authors:  Helen P Price; M Lucia S Güther; Michael A J Ferguson; Deborah F Smith
Journal:  Mol Biochem Parasitol       Date:  2009-09-24       Impact factor: 1.759
  7 in total

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