| Literature DB >> 2035992 |
Abstract
Hypothalamic-pituitary-adrenocortical (HPA) physiology is complex, and dysregulation of this neuroendocrine axis cannot be characterized adequately by isolated or unintegrated measures. Repeated assessments over time, involving multiple measures of axis activity (basal and dynamic tests), have furthered our understanding of the character of the HPA abnormalities reported in various psychiatric disorders. We review the nature and clinical significance of these HPA disturbances in the affective disorders and other psychiatric illnesses.Entities:
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Year: 1991 PMID: 2035992 DOI: 10.1146/annurev.me.42.020191.002511
Source DB: PubMed Journal: Annu Rev Med ISSN: 0066-4219 Impact factor: 13.739