| Literature DB >> 20359004 |
Jae-Hyung Kim1, Kwan-Pyo Cho, Young-Suk Chung, Ok-Su Kim, Sung-Soo Chung, Kyung-Ku Lee, Doh-Jae Lee, Kwang-Min Lee, Young-Joon Kim.
Abstract
The biological response of fetal rat calvarial cells on a TiO2 nanotubular surface (Ti-NT) was evaluated by cell viability assay, alkaline phosphatase (ALP) activity and reverse transcription polymerase chain reaction (RT-PCR) analysis. The cell viability assay showed no significant difference between the Ti-NT and smooth titanium surfaces (Ti-S). Ti-NT had better cellular responses with regard to the ALP activity and bone-associated markers, such as bone sialoprotein and osteocalcin mRNA than Ti-S. These results suggest that Ti-NT stimulate the differentiation into osteoblasts of fetal rat calvarial cells, potentially contributing to rapid osseointegration.Entities:
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Year: 2010 PMID： 20359004 DOI： 10.1166/jnn.2010.2235
Source DB: PubMed Journal: J Nanosci Nanotechnol ISSN： 1533-4880