Literature DB >> 20358942

Folate conjugated poly(ester amine) for lung cancer therapy.

Rohidas B Arote1, Mi-Kyong Yoon, Tae-Hee Kim, Dhananjay Jere, Hu-Lin Jiang, You-Kyoung Kim, In-Kyu Park, Chong-Su Cho.   

Abstract

Folate conjugated poly(ester amine) (PEA) was prepared by reaction of folic acid with PEAs based on polycaprolactone (PCL) and low molecular weight polyethylenimine (LMW-PEI) with PEG as a linker. This novel gene carrier showed excellent physicochemical properties and relatively low cytotoxicity compared with PEI 25K. It showed excellent transfection efficiency through folate receptor mediated endocytosis.

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Year:  2010        PMID: 20358942     DOI: 10.1166/jnn.2010.2239

Source DB:  PubMed          Journal:  J Nanosci Nanotechnol        ISSN: 1533-4880


  1 in total

1.  Development of novel, biocompatible, polyester amines for microglia-targeting gene delivery.

Authors:  Boomin Choi; Min-Hye Ahn; Seojin Hong; Ellane Eda Barcelon; Jaiprakash Sangshetti; Rohidas B Arote; Sung Joong Lee
Journal:  RSC Adv       Date:  2021-11-16       Impact factor: 4.036

  1 in total

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