Eruptive syringoma in a patient with trisomy 21.

Syringomas are benign adnexal neoplasia that are classified into four main types, according to their clinical features and associations. Syringoma associated with trisomy 21 typically presents with a periorbital cutaneous involvement. We report an 18-year-old Chinese girl with trisomy 21, who presented with eruptive syringoma, an unusual generalised form involving her trunk and limbs. A histological examination was performed to confirm the diagnosis.