Literature DB >> 20356695

D225G mutation in the hemagglutinin protein found in 3 severe cases of 2009 pandemic influenza A (H1N1) in Spain.

Andrés Antón1, María Angeles Marcos, Miguel Julián Martínez, Susana Ramón, Anna Martínez, Neus Cardeñosa, Pere Godoy, Nuria Torner, Patricia De Molina, Ricard Isanta, María Teresa Jiménez de Anta, Tomàs Pumarola.   

Abstract

From 27 April to 16 December 2009, we analyzed the hemagglutinin gene sequence of 2009 pandemic influenza A (H1N1) virus in 189 respiratory specimens. We only found the D225G mutation in 3 severe cases. However, it was not found in samples from other cases with or without clinical criteria of severity. The biologic significance of this mutation remains still unclear. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20356695     DOI： 10.1016/j.diagmicrobio.2010.02.002

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  10 in total

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  10 in total

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