| Literature DB >> 20356064 |
M Iqbal Choudhary1, Muhammad Ismail, Khozirah Shaari, Ahmed Abbaskhan, Samina A Sattar, Nordin H Lajis.
Abstract
Phytochemical and cytotoxicity investigations on organic solvent extracts of the aerial parts of Tinospora crispa have led to the isolation of 15 cis-clerodane-type furanoditerpenoids. Of these, nine compounds (1-9) were found to be new. Spectroscopic assignments of a previously reported compound, borapetoside A (13), were revised on the basis of HMQC and HMBC correlations. No discernible activity was observed when compounds 10-13 were subjected to evaluation in cytotoxicity assays against human prostate cancer (PC-3) and the normal mouse fibroblast (3T3) cell lines.Entities:
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Year: 2010 PMID： 20356064 DOI： 10.1021/np900551u
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050