| Literature DB >> 20354890 |
Shiomi Yoshida1, Katsuhiro Suzuki, Tomotada Iwamoto, Kazunari Tsuyuguchi, Motohisa Tomita, Masaji Okada, Mitsunori Sakatani.
Abstract
We compared rifabutin susceptibility and rpoB mutations in 98 multi-drug-resistant strains of Mycobacterium tuberculosis (MDR-TB) by DNA sequencing and with a line probe assay using the commercially available INNO-LiPA Rif. TB kit (the LiPA). Our results indicated that rifabutin continues to remain active against MDR-TB strains harboring certain genetic alterations and also that the LiPA might be useful in identifying MDR-TB strains susceptible to rifabutin.Entities:
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Year: 2010 PMID: 20354890 DOI: 10.1007/s10156-010-0057-5
Source DB: PubMed Journal: J Infect Chemother ISSN: 1341-321X Impact factor: 2.211