Literature DB >> 20353641

Can the National Health Service Cancer Plan timeline be applied to colorectal hepatic metastases?

Claire Jones1, Stephen A Badger, Jane McClements, Lloyd McKie, Tom Diamond, Mark A Taylor.   

Abstract

INTRODUCTION: The National Health Service (NHS) Cancer Plan guidelines recommend a maximum 2-week wait from referral to first appointment, and 2 months from referral to treatment for primary cancers. However, there are currently no guidelines available for metastatic disease. In the UK, nearly half of all colorectal cancer patients develop hepatic metastases. Timely, surgical resection offers the potential for cure. The aim of this study was to audit current practice for colorectal liver metastases in a regional hepatobiliary unit, and compare this to the NHS Cancer Plan standards for primary disease. PATIENTS AND METHODS: A retrospective review of the unit's database was performed for all hepatic metastases referrals from January 2006 to December 2008. The dates of referral, first appointment, investigations and initiation of treatment, along with patient's age and sex, were recorded on Microsoft Excel and analysed. Time was expressed as mean +/- SD in days.
RESULTS: A total of 102 patients with hepatic metastases were identified. Five were excluded due to incomplete data. The average time from referral to first appointment was 10.6 +/- 9.4 days and the average time from referral to treatment was 38.5 +/- 28.6 days. Seventy-five (72.7%) had surgical intervention, of whom 37 also had chemotherapy.
CONCLUSIONS: The data compare favourably to the NHS Cancer Plan guidelines for primary malignancy, demonstrating that a regional hepatobiliary unit is capable of delivering a service for colorectal liver metastases that adheres to the NHS Cancer Plan. Therefore, the NHS Cancer Plan can be applied to this cohort.

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Year:  2010        PMID: 20353641      PMCID: PMC3025242          DOI: 10.1308/003588410X12628812458734

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  11 in total

1.  Neoadjuvant chemotherapy for unresectable liver metastases of colorectal cancer--too good to be true?

Authors:  M M Borner
Journal:  Ann Oncol       Date:  1999-06       Impact factor: 32.976

2.  Guidelines for resection of colorectal cancer liver metastases.

Authors:  O J Garden; M Rees; G J Poston; D Mirza; M Saunders; J Ledermann; J N Primrose; R W Parks
Journal:  Gut       Date:  2006-08       Impact factor: 23.059

3.  Colorectal liver metastases: CT, MR imaging, and PET for diagnosis--meta-analysis.

Authors:  Shandra Bipat; Maarten S van Leeuwen; Emile F I Comans; Milan E J Pijl; Patrick M M Bossuyt; Aeilko H Zwinderman; Jaap Stoker
Journal:  Radiology       Date:  2005-08-11       Impact factor: 11.105

4.  Evaluation of long-term survival after hepatic resection for metastatic colorectal cancer: a multifactorial model of 929 patients.

Authors:  Myrddin Rees; Paris P Tekkis; Fenella K S Welsh; Thomas O'Rourke; Timothy G John
Journal:  Ann Surg       Date:  2008-01       Impact factor: 12.969

5.  Surgical treatment for better prognosis of patients with liver metastases from colorectal cancer.

Authors:  Nobuhiko Taniai; Koho Akimaru; Hiroshi Yoshida; Takashi Tajiri
Journal:  Hepatogastroenterology       Date:  2007-09

6.  Resource and manpower calculations for the provision of hepatobiliary surgical services in the UK.

Authors:  Ali W Majeed; Charles Price
Journal:  Ann R Coll Surg Engl       Date:  2004-03       Impact factor: 1.891

7.  Liver surgery for colorectal metastases: results after 10 years of follow-up. Long-term survivors, late recurrences, and prognostic role of morbidity.

Authors:  Luca Viganò; Alessandro Ferrero; Roberto Lo Tesoriere; Lorenzo Capussotti
Journal:  Ann Surg Oncol       Date:  2008-05-08       Impact factor: 5.344

8.  Survival after hepatic resection for colorectal metastases: a 10-year experience.

Authors:  Alice C Wei; Paul D Greig; David Grant; Bryce Taylor; Bernard Langer; Steven Gallinger
Journal:  Ann Surg Oncol       Date:  2006-03-10       Impact factor: 5.344

9.  A 10-year study of outcome following hepatic resection for colorectal liver metastases - The effect of evaluation in a multidisciplinary team setting.

Authors:  J T Lordan; N D Karanjia; N Quiney; W J Fawcett; T R Worthington
Journal:  Eur J Surg Oncol       Date:  2008-03-06       Impact factor: 4.424

10.  An update and our experience with metastatic liver disease.

Authors:  Mahim Koshariya; Rajan B Jagad; Jun Kawamoto; P Papastratis; H Kefalourous; T Porfiris; Christina Tzouma; N J Lygidakis
Journal:  Hepatogastroenterology       Date:  2007-12
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